Baumgartner A, Grzejszczyk G, Klink F, Oberheuser F, Rehder H
Zentralbl Gynakol. 1986;108(16):990-4.
The Ivemark-Syndrome (Alienie Syndrome) is defined by the characteristic association of splenic aplasia, organsymmetry and other malformations especially of the cardiovascular system. More than 200 cases are reported. The incidence of Ivemark-Syndrome is very low. The aetiology is not yet clearly defined. As a main cause exogen factors between the 31st and 38th day of gestation are discussed, but a genetic cause has not been detected yet. Due to the unfavourable prognosis an intensive ultrasonographic screening is to be asked for.
伊韦马克综合征（无脾综合征）的定义为脾发育不全、器官对称以及特别是心血管系统的其他畸形的特征性关联。已报告200多例病例。伊韦马克综合征的发病率非常低。病因尚未明确界定。作为主要原因，讨论了妊娠第31天至第38天之间的外源性因素，但尚未检测到遗传原因。由于预后不佳，需要进行强化超声筛查。
