Department of Psycho-oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, China.
Department of Outpatient, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Psychooncology. 2022 Aug;31(8):1302-1312. doi: 10.1002/pon.5932. Epub 2022 Apr 4.
The aims of this study were to explore the frequency of somatic symptom disorder (SSD) and the relationship between SSD and somatic, psychological, and social factors in Chinese patients with breast cancer.
This multicenter cross-sectional study enrolled 264 patients with breast cancer from three different departments in Beijing. The structured clinical interview for fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (SCID-5) for SSD. Standardized questionnaires and clinical data were used to compare patients with and without SSD.
Somatic symptom disorder was diagnosed in 21.6% (57/264) of all enrolled patients. No differences were found between SSD patients and non-SSD patients in terms of sociodemographic characteristics and tumor-specific variables, except radiotherapy. However, patients with SSD reported higher levels of depression, anxiety and cancer-related worry. They also showed a longer duration of symptoms, greater impairment in daily life, more concern over their physical complaints and more doctor visits. In a stepwise binary logistic regression analysis, among others, higher health anxiety (WI-8, Exp(B) = 0.107, p = 0.009) and more doctor visits (OR = -1.841, p < 0.001) showed a significant association with SSD; the model explained 53.7% of the variance.
Similar to other physical diseases, there is a high prevalence of SSD in patients with breast cancer. Somatic symptom disorder patients differ from non-SSD patients by exhibiting higher cancer-related emotional distress and dysfunctional illness perception and behavior. There remain substantial challenges in the diagnosis of SSD in patients with cancer and other medical conditions.
ChiCTR2100051525.
本研究旨在探讨躯体症状障碍（SSD）在我国乳腺癌患者中的发生频率，以及 SSD 与躯体、心理和社会因素的关系。
本多中心横断面研究纳入了来自北京三家不同科室的 264 例乳腺癌患者。采用第五版《精神障碍诊断与统计手册》（DSM-5）结构临床访谈（SCID-5）对 SSD 进行诊断。使用标准化问卷和临床数据比较了 SSD 患者和非 SSD 患者。
所有入组患者中，21.6%（57/264）被诊断为 SSD。除放疗外，SSD 患者和非 SSD 患者在社会人口统计学特征和肿瘤特异性变量方面无差异。然而，SSD 患者报告的抑郁、焦虑和与癌症相关的担忧程度更高。他们的症状持续时间更长，日常生活受损更严重，对身体抱怨的关注更多，就诊次数更多。在逐步二元逻辑回归分析中，除其他因素外，较高的健康焦虑（WI-8，Exp(B)=0.107，p=0.009）和更多的就诊次数（OR=-1.841，p<0.001）与 SSD 显著相关；该模型解释了 53.7%的方差。
与其他躯体疾病一样，乳腺癌患者中 SSD 的患病率较高。SSD 患者与非 SSD 患者不同，表现为更高的与癌症相关的情绪困扰和功能失调的疾病感知和行为。在癌症和其他医疗条件患者中诊断 SSD 仍存在很大挑战。
ChiCTR2100051525。
