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肝移植受者免疫抑制治疗依从性与精神幸福感调查。

Investigation of adherence to immunosuppressive therapy and spiritual well-being in liver recipients.

机构信息

Division of Surgical Nursing, Nursing Department, Health Sciences Faculty, Bayburt University, Bayburt, Turkey.

Division of Surgical Nursing, Nursing Department, Health Sciences Faculty, Istanbul Aydin University, Istanbul, Turkey.

出版信息

Transpl Immunol. 2022 Jun;72:101585. doi: 10.1016/j.trim.2022.101585. Epub 2022 Mar 28.

Abstract

OBJECTIVE

In our study, we investigated the relationship between spiritual well-being and adherence to immunosuppressive therapy after liver transplantation.

METHOD

We conducted this descriptive and cross-sectional study with the participation of 131 liver transplant recipients after they had received their transplants. Data collection was carried out using a Personal Information Form, the Spiritual Well-Being Scale and the Immunosuppressant Therapy Adherence Scale. The IBM Statistical Package for the Social Sciences 25.0 was used for the statistical analyses.

RESULTS

While 73.3% of the patients were at the ages of 45-64, 72.5% were male, and 39.7% had been using immunosuppressive medication for a period between 6 months and 1 year. The rate of corticosteroid use among the patients was 30.5%, and the rate of antimetabolite use was 21.4%. A positive and significant relationship was found between adherence to immunosuppressive treatment and spiritual well-being (B = 0.425, p = 0.017).

CONCLUSION

Spiritual well-being is an inexpensive, effective and easy strategy to increase adherence to immunosuppressive treatment. Awareness should be raised in physicians and nurses about the importance of spiritual well-being, and they should be encouraged to support spiritual well-being.

摘要

目的

在本研究中,我们调查了肝移植后精神幸福感与免疫抑制治疗依从性之间的关系。

方法

我们进行了这项描述性和横断面研究,共纳入 131 名肝移植受者。数据收集采用个人信息表、精神幸福感量表和免疫抑制剂治疗依从性量表进行。采用 IBM SPSS 25.0 进行统计分析。

结果

73.3%的患者年龄在 45-64 岁之间,72.5%为男性,39.7%使用免疫抑制剂的时间在 6 个月至 1 年之间。患者中皮质类固醇的使用率为 30.5%,抗代谢物的使用率为 21.4%。免疫抑制治疗的依从性与精神幸福感呈正相关(B=0.425,p=0.017)。

结论

精神幸福感是提高免疫抑制治疗依从性的一种廉价、有效且简单的策略。应提高医生和护士对精神幸福感重要性的认识,并鼓励他们支持精神幸福感。

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