Liu Bao-Peng, Qin Ping, Zhang Jie, Hennessy Dwight A, Chu Jie, Wang Xin-Ting, Wei Yan-Xin, Jia Cun-Xian
Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; Center for Suicide Prevention Research, Shandong University, Jinan, Shandong, China.
National Centre for Suicide Research and Prevention, Institute of Clinical Medicine of University of Oslo, Oslo, Norway.
J Psychiatr Res. 2022 Jun;150:71-78. doi: 10.1016/j.jpsychires.2022.03.034. Epub 2022 Mar 23.
Previous suicide attempt is a strong risk factor for subsequent suicide and other causes of mortality, but evidence from China is sparse. In this study, follow up face-to-face interviews were conducted with suicide attempters or a key informant, and any subsequent deaths were examined through local cause-of-death censoring databases to ascertain details surrounding the death. Competitive risk models and Cox proportional hazard regression models were used to ascertain significant risk factors of suicide, non-suicide and overall deaths following suicide attempt. Predictive nomograms were also constructed to predict the probability of suicide, non-suicide, and overall deaths. A total of 1103 suicide attempters were successfully interviewed with an average follow-up time of 7.48 (7.38-7.57) years. The cumulative rates of suicide at 1, 2, 3, 5 and 10 years were 0.27%, 0.63%, 0.91%, 1.56%, and 1.83%, respectively. Factors significantly associated with subsequent suicide were advancing age, history of suicide attempt, and mental disorders. Significant risk factors for non-suicide death included males, advancing age, and physical illness. Overall deaths during the follow-up period were associated with males, advancing age, physical illness, and mental disorders. Predictive models showed good ability with satisfactory C-indexes (between 0.77 and 0.86) and excellent calibration performance in predicting the varying causes of subsequent death among suicide attempters in rural China.
既往自杀未遂是随后自杀及其他死亡原因的一个重要风险因素,但来自中国的证据较少。在本研究中,对自杀未遂者或一名关键信息提供者进行了随访面对面访谈,并通过当地死因审查数据库对任何随后的死亡情况进行了调查,以确定死亡相关细节。采用竞争风险模型和Cox比例风险回归模型来确定自杀未遂后自杀、非自杀及全因死亡的重要风险因素。还构建了预测列线图以预测自杀、非自杀及全因死亡的概率。共成功访谈了1103名自杀未遂者,平均随访时间为7.48(7.38 - 7.57)年。1年、2年、3年、5年和10年的累积自杀率分别为0.27%、0.63%、0.91%、1.56%和1.83%。与随后自杀显著相关的因素包括年龄增长、自杀未遂史和精神障碍。非自杀死亡的重要风险因素包括男性、年龄增长和躯体疾病。随访期间的全因死亡与男性、年龄增长、躯体疾病和精神障碍有关。预测模型显示出良好的能力,C指数令人满意(在0.77至0.86之间),并且在预测中国农村自杀未遂者随后不同死亡原因方面具有出色的校准性能。