Andrology & STDs Department, KasrAlAiny Faculty Of Medicine, Cairo, Egypt.
Adam International Hospital, Giza, Egypt.
Reprod Sci. 2022 Jun;29(6):1836-1843. doi: 10.1007/s43032-022-00927-w. Epub 2022 Mar 31.
We aimed to find a correlation between the intraoperative diameters of the seminiferous tubules evaluated at high magnification during micro-testicular sperm extraction (micro-TESE) and total motile sperm count (TMSC) in non-obstructive azoospermic (NOA) patients. Five hundred four consecutive NOA patients were included and underwent micro-TESE. The change in the mean TMSC and different seminiferous tubular diameters was of high statistical significance (p < 0.001). It should be noted that the highest mean TMSC was reported in the dilated tubules (DTs) group followed by the other study groups 941.72 ± 196.97, 487.37 ± 443.57, and 34.54 ± 60.79, respectively. Furthermore, 21 naïve cases had dilated tubules (DTs) and 18 (85.7%) of them had shown eventful micro-TESE. Conversely, 186 naïve cases had slightly dilated tubules (SDTs), and 101 (54.3%) of them had eventful micro-TESE. Only 8 (24.25%) cases of the 33 cases had non dilated tubules (NDTs) and showed eventful micro-TESE. The frequency of intrasurgical seminiferous tubular diameter and micro-TESE outcome among the naïve cases had demonstrated a highly statistical significance (p < 0.001). Interestingly, all salvaged cases (100%) with DTs and a previous eventful TESE had shown eventful TESE in the current study. The most dilated intrasurgical seminiferous tubular diameter is associated with the highest TMSC in NOA patients including SCO cases.
我们旨在寻找在非梗阻性无精子症（NOA）患者的显微睾丸精子提取（micro-TESE）中高倍放大评估的生精小管术中直径与总运动精子计数（TMSC）之间的相关性。504 例连续的 NOA 患者接受了 micro-TESE 治疗。平均 TMSC 和不同生精小管直径的变化具有高度统计学意义（p<0.001）。值得注意的是，在扩张的小管（DTs）组中报告了最高的平均 TMSC，随后是其他研究组，分别为 941.72±196.97、487.37±443.57 和 34.54±60.79。此外，21 例初治患者有扩张的小管（DTs），其中 18 例（85.7%）显示有意义的 micro-TESE。相反，186 例初治患者有轻微扩张的小管（SDTs），其中 101 例（54.3%）显示有意义的 micro-TESE。在 33 例中有非扩张的小管（NDTs）的病例中，只有 8 例（24.25%）显示有意义的 micro-TESE。初治患者的术中生精小管直径和 micro-TESE 结果的频率具有高度统计学意义（p<0.001）。有趣的是，在当前研究中，所有带有 DTs 的挽救病例（100%）和之前有意义的 TESE 都显示出了有意义的 TESE。在包括 SCO 病例在内的 NOA 患者中，最扩张的术中生精小管直径与最高的 TMSC 相关。
