Blank Jonathon, Blomquist Matthew, Arant Lesley, Cone Stephanie, Roth Joshua
Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Ann Biomed Eng. 2022 Jul;50(7):751-768. doi: 10.1007/s10439-022-02935-y. Epub 2022 Mar 31.
Developing methods for the non-invasive characterization of the mechanics of musculoskeletal tissues is an ongoing research focus in biomechanics. Often, these methods use the speed of shear wave propagation to characterize tissue mechanics (e.g., shear wave elastography and shear wave tensiometry). The primary purpose of this systematic review was to identify, compare, and contrast current methods for exciting and measuring shear wave propagation in musculoskeletal tissues. We conducted searches in the Web of Science, PubMed, and Scopus databases for studies published from January 1, 1900, to May 1, 2020. These searches targeted both shear wave excitation using acoustic pushes and mechanical taps, and shear wave speed measurement using ultrasound, magnetic resonance imaging, accelerometers, and laser Doppler vibrometers. Two reviewers independently screened and reviewed the articles, identifying 524 articles that met our search criteria. Regarding shear wave excitation, we found that acoustic pushes are useful for exciting shear waves through the thickness of the tissue of interest, and mechanical taps are useful for exciting shear waves in wearable applications. Regarding shear wave speed measurement, we found that ultrasound is used most broadly to measure shear waves due to its ability to study regional differences and target specific tissues of interest. The strengths of magnetic resonance imaging, accelerometers, and laser Doppler vibrometers make them advantageous to measure shear wave speeds for high-resolution shear wave imaging, wearable measurements, and non-contact ex vivo measurements, respectively. The advantages that each method offers for exciting and measuring shear waves indicate that a variety of systems can be assembled using currently available technologies to determine musculoskeletal tissue material behavior across a range of innovative applications.
开发用于非侵入性表征肌肉骨骼组织力学特性的方法是生物力学领域持续关注的研究重点。通常，这些方法利用剪切波传播速度来表征组织力学特性（例如，剪切波弹性成像和剪切波张力测量法）。本系统综述的主要目的是识别、比较和对比当前用于激发和测量肌肉骨骼组织中剪切波传播的方法。我们在科学网、PubMed和Scopus数据库中检索了1900年1月1日至2020年5月1日发表的研究。这些检索针对使用声推动和机械轻敲进行的剪切波激发，以及使用超声、磁共振成像、加速度计和激光多普勒振动计进行的剪切波速度测量。两名评审员独立筛选和评审文章，共识别出524篇符合我们检索标准的文章。关于剪切波激发，我们发现声推动有助于激发感兴趣组织厚度方向的剪切波，而机械轻敲在可穿戴应用中激发剪切波很有用。关于剪切波速度测量，我们发现超声由于能够研究区域差异并针对特定感兴趣组织，因此被最广泛地用于测量剪切波。磁共振成像、加速度计和激光多普勒振动计的优势分别使其有利于进行高分辨率剪切波成像、可穿戴测量和非接触离体测量的剪切波速度测量。每种方法在激发和测量剪切波方面所具有的优势表明，可以利用现有技术组装各种系统，以确定一系列创新应用中的肌肉骨骼组织材料行为。
