Haas R J, Rieber P, Helmig M, Strobel E, Belohradsky B H, Heim M U
Blut. 1986 Nov;53(5):401-4. doi: 10.1007/BF00321102.
In ABO mismatched organ or bone marrow transplants recently some cases of acquired immune hemolysis have been reported. It was felt that these life threatening complications were due to immunosuppressive treatment with cyclosporin-A. A case of severe hemolysis following mismatched BMT is reported. Here no cyclosporin-A treatment was given since the bone marrow was T-cell deprived by an E-rosetting technique. Apparently T-cell purging can under these conditions become dangerous.
在ABO血型不匹配的器官或骨髓移植中，最近已有一些获得性免疫性溶血病例的报道。据认为，这些危及生命的并发症是由于使用环孢素A进行免疫抑制治疗所致。本文报告了1例不匹配骨髓移植后发生严重溶血的病例。由于采用E花环技术去除了骨髓中的T细胞，因此未给予环孢素A治疗。显然，在这些情况下，T细胞清除可能会变得危险。
