Does viloxazine really improve sex drive? A double-blind controlled study.

The action of viloxazine on libido and sex drive was evaluated with a randomised controlled double-blind trial against placebo on a population of 26 male out-patients affected by primary depression (DSM III). Modifications in the sexual sphere were assessed by the ad hoc inclusion of a series of items in the Zung Self-Rating Depression Scale. Thus modified, the scale was administered at the beginning and the end of a four-week trial period. Viloxazine proved to have a considerable disinhibiting effect, whose principal expression level was a return to pre-depression levels of frequency in sexual relations.