Wang Jiao, Yang Qing, Wang Dandan, Li Mengyuan, Zhang Ningning
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Front Med (Lausanne). 2022 Mar 8;9:845445. doi: 10.3389/fmed.2022.845445. eCollection 2022.
Gastric-type endocervical adenocarcinoma (GAS) is considered a distinct and clinically important entity because it is unrelated to human papillomavirus infection and has aggressive behavior and worse clinical outcomes than the usual type of endocervical adenocarcinoma (ECA). The preoperative diagnosis of GAS is often difficult because of its nonspecific clinical manifestations and special lesion location. We report the case of a 50-year-old Chinese woman who presented with intermittent left lower abdominal pain for 1 year. Preoperative images showed left hydrosalpinx and a lesion that was mainly located in the lower part of the uterine cavity. We considered the lesion to be a polyp before surgery. During hysteroscopic surgery, we suspected that it may be a submucosal myoma. However, pathology revealed that it was a GAS. GAS may be located in the upper endocervix or even reach the uterine cavity. The appearance is occasionally similar to that of submucosal myoma, resulting in difficult preoperative diagnosis and even misdiagnosis.
胃型宫颈腺癌(GAS)被认为是一种独特且具有临床重要性的实体,因为它与人类乳头瘤病毒感染无关,具有侵袭性的行为,并且与普通类型的宫颈腺癌(ECA)相比临床结局更差。由于其非特异性的临床表现和特殊的病变位置,GAS的术前诊断往往很困难。我们报告了一例50岁中国女性的病例,该患者出现间歇性左下腹疼痛1年。术前影像显示左侧输卵管积水以及一个主要位于子宫腔下部的病变。手术前我们认为该病变是一个息肉。在宫腔镜手术期间,我们怀疑它可能是一个黏膜下肌瘤。然而,病理显示它是一个胃型宫颈腺癌。胃型宫颈腺癌可能位于宫颈上段,甚至可延伸至子宫腔。其外观偶尔与黏膜下肌瘤相似,导致术前诊断困难甚至误诊。