Rampal Sanjiv, Jaiman Ashish, Tokgöz Mehmet Ali, Arumugam Gayathri, Sivananthan Sureshan, Singh Rashdeep Singh Jagdeb, Zazali Syafiqah Binti, Mohaddes Maziar
Department of Orthopaedic, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Jt Dis Relat Surg. 2022;33(1):255-262. doi: 10.52312/jdrs.2022.402. Epub 2022 Mar 28.
Hip injection (HI) for osteoarthritis (OA) are in vogue nowadays. Corticosteroids (CSs) and hyaluronic acid (HA) gel are the two most common agents injected into the hip. Off late, platelet-rich plasma (PRP), mesenchymal stem cell (MSC), bone marrow aspirate concentrate (BMAC), local anesthetic (LA) agents, non-steroidal anti-inflammatory drugs (NSAIDs) and their different combinations have also been injected in hips to provide desired pain relief. However, there is a group of clinicians who vary of these injections. A search of the literature was performed on PubMed, Cochrane Library, and DOAJ using the keywords "hip osteoarthritis injection". Data were analyzed and compiled. Intraarticular CSs are effective in providing the desired pain relief in OA hip, but repeated injections should be avoided and the interval between HI and hip arthroplasty must be kept for more than three months. Methylprednisolone or triamcinolone are combined with 1% lidocaine or 0.5% bupivacaine. Chondrotoxic effects of LA is a concern. Although national guidelines do not favor the use of HA for hip OA, numerous publications have favored its usage for a moderate grade of OA. The PRP, MSC, and BMAC are treatment options with great potential; however, currently, the evidence is conflicting on their role in hip OA. There is always a risk of septic arthritis, particularly when aseptic precautions are not followed, and clinicians must vary of this complication.
髋关节注射(HI)治疗骨关节炎(OA)目前很流行。皮质类固醇(CSs)和透明质酸(HA)凝胶是注入髋关节最常用的两种药物。最近,富血小板血浆(PRP)、间充质干细胞(MSC)、骨髓抽吸浓缩物(BMAC)、局部麻醉剂(LA)、非甾体抗炎药(NSAIDs)及其不同组合也被注入髋关节以提供所需的疼痛缓解。然而,有一组临床医生对这些注射方法存在疑虑。使用关键词“髋关节骨关节炎注射”在PubMed、Cochrane图书馆和DOAJ上进行了文献检索。对数据进行了分析和整理。关节内注射CSs对缓解OA髋关节的疼痛有效,但应避免重复注射,HI与髋关节置换术之间的间隔必须保持三个月以上。甲泼尼龙或曲安奈德与1%利多卡因或0.5%布比卡因联合使用。LA的软骨毒性作用是一个问题。尽管国家指南不赞成将HA用于髋关节OA,但许多出版物赞成将其用于中度OA。PRP、MSC和BMAC是具有巨大潜力的治疗选择;然而,目前关于它们在髋关节OA中的作用的证据存在矛盾。总有发生化脓性关节炎的风险,尤其是在不遵循无菌预防措施时,临床医生必须警惕这种并发症。