Department of General, Vascular and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland.
Department of Medical Informatics and Telemedicine, Medical University of Warsaw, Warsaw, Poland.
Med Sci Monit. 2022 Apr 1;28:e936272. doi: 10.12659/MSM.936272.
BACKGROUND Laparoscopic adrenalectomy is acknowledged as a standard procedure in adrenal lesions management. This retrospective study of lateral transabdominal laparoscopic adrenalectomy performed between 1997 and 2017 in a single center in Poland aimed to determine the factors associated with surgery time. MATERIAL AND METHODS This retrospective study involved 881 patients. The factors identified as potentially affecting surgery time were age, sex, side of the lesion, histopathological type, hormonal activity, size of the lesion, history of previous abdominal operations, presence of intra-abdominal adhesions, and obesity. The following statistical tests were conducted: t test, Mann-Whitney U test, Kruskal-Wallis H test, Pearson correlation test, and multivariate regression modeling. RESULTS The mean surgery time for all operations was 139 min (55-320 min). We observed statistically significant differences for surgery time in the following groups: sex, side of the lesion, presence of intra-abdominal adhesions, obesity, histopathological type, and hormonal activity (P<0.05). The multivariate regression model showed factors affecting surgery time were: sex, side of the lesion, size of the lesion, obesity, histopathological type (nodular hyperplasia and adenoma), and hormonal activity (non-functioning and aldosterone-secreting tumors) (P<0.05). There was no correlation between surgery time and patient age and tumor size (P<0.05). Mean tumor size was 42 mm (6-130 mm). CONCLUSIONS The 20-year experience of laparoscopic adrenalectomy performed at a single center showed that surgery duration was significantly longer in male patients, obese patients, left-sided adrenal tumors, tumors >6 cm in diameter, patients with a diagnosis of pheochromocytoma, and when intra-abdominal adhesions were present.
腹腔镜肾上腺切除术已被公认为治疗肾上腺病变的标准方法。本研究回顾性分析了 1997 年至 2017 年间在波兰一家中心进行的经侧腹腹腔镜肾上腺切除术,旨在确定与手术时间相关的因素。
本回顾性研究纳入了 881 例患者。确定可能影响手术时间的因素包括年龄、性别、病变侧、组织病理学类型、激素活性、病变大小、既往腹部手术史、腹腔内粘连存在情况和肥胖。进行了 t 检验、Mann-Whitney U 检验、Kruskal-Wallis H 检验、Pearson 相关检验和多变量回归建模。
所有手术的平均手术时间为 139 分钟(55-320 分钟)。我们观察到手术时间在以下组间存在统计学显著差异:性别、病变侧、腹腔内粘连存在情况、肥胖、组织病理学类型和激素活性(P<0.05)。多变量回归模型显示影响手术时间的因素包括:性别、病变侧、病变大小、肥胖、组织病理学类型(结节性增生和腺瘤)和激素活性(无功能和醛固酮分泌肿瘤)(P<0.05)。手术时间与患者年龄和肿瘤大小之间无相关性(P<0.05)。平均肿瘤大小为 42 毫米(6-130 毫米)。
单中心 20 年腹腔镜肾上腺切除术经验表明,男性患者、肥胖患者、左侧肾上腺肿瘤、直径>6 厘米的肿瘤、诊断为嗜铬细胞瘤的患者以及存在腹腔内粘连时,手术时间显著延长。