Division of Neonatology, Baylor University Medical Center, and Pediatrix Medical Group of Dallas, Dallas, TX.
Division of Neonatology, Kaiser Permanente Moanalua Medical Center, Honolulu, HI.
Neoreviews. 2022 Apr 1;23(4):e250-e261. doi: 10.1542/neo.23-4-e250.
Before 2015, major changes in Neonatal Resuscitation Program (NRP) recommendations not supporting previously endorsed antepartum, intrapartum and postpartum interventions to prevent meconium aspiration syndrome were based on adequately powered multicenter randomized controlled trials. The 2015 and 2020 American Heart Association guidelines and 7th and 8th edition of NRP suggest not performing routine intubation and tracheal suctioning of nonvigorous meconium-stained newborns. However, this was given as a weak recommendation with low-certainty evidence. The purpose of this review is to summarize the evidence and explore the question of appropriate delivery room management for nonvigorous meconium-stained newborns.
在 2015 年之前，新生儿复苏计划 (NRP) 建议的重大变化并未支持先前认可的用于预防胎粪吸入综合征的产前、产时和产后干预措施，这些变化是基于充分有力的多中心随机对照试验。2015 年和 2020 年美国心脏协会指南以及 NRP 的第 7 版和第 8 版建议不对非活力胎粪污染的新生儿进行常规插管和气管抽吸。然而，这只是一个弱推荐，证据确定性低。本综述的目的是总结证据，并探讨非活力胎粪污染新生儿的产房处理问题。
