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艾滋病毒感染者在佛罗里达州 Ryan White 计划中自诊断以来的 HIV 护理参与的纵向轨迹。

Longitudinal trajectories of HIV care engagement since diagnosis among persons with HIV in the Florida Ryan White program.

机构信息

Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, 2004 Mowry Road, PO Box 100231, 32610-0231, Gainesville, FL, United States.

Department of Health Outcome and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, United States.

出版信息

AIDS Behav. 2022 Oct;26(10):3164-3173. doi: 10.1007/s10461-022-03659-9. Epub 2022 Apr 1.

Abstract

HIV care engagement is a dynamic process. We employed group-based trajectory modeling to examine longitudinal patterns in care engagement among people who were newly diagnosed with HIV and enrolled in the Ryan White program in Florida (n = 9,755) between 2010 and 2015. Five trajectories were identified (47.9% "in care" with 1-2 care visit(s) per 6 months, 18.0% "frequent care" with 3 or more care visits per 6 months, 11.0% "re-engage", 11.0% "gradual drop out", 12.6% "early dropout") based on the number of care attendances (including outpatient/case management visits, viral load or CD4 test) for each six-month during the first five years since diagnosis. Relative to "in care", people in the "frequent care" trajectory were more likely to be Hispanic/Latino and older at HIV diagnosis, whereas people in the three suboptimal care retention trajectories were more likely to be younger. Area deprivation index, rurality, and county health rankings were also strongly associated with care trajectories. Individual- and community-level factors associated to the three suboptimal care retention trajectories, if confirmed to be causative and actionable, could be prioritized to improve HIV care engagement.

摘要

艾滋病毒护理参与是一个动态的过程。我们采用基于群组的轨迹建模方法,研究了 2010 年至 2015 年间佛罗里达州新诊断出艾滋病毒并参加瑞安·怀特计划的人群(n=9755)在护理参与方面的纵向模式。根据诊断后五年内每六个月的护理就诊次数(包括门诊/病例管理就诊、病毒载量或 CD4 检测),确定了五个轨迹(47.9%的人“在护理中”,每 6 个月有 1-2 次护理就诊,18.0%的人“频繁护理”,每 6 个月有 3 次或更多护理就诊,11.0%的人“重新参与”,11.0%的人“逐渐退出”,12.6%的人“早期退出”)。与“在护理中”的人相比,“频繁护理”轨迹中的人更有可能是西班牙裔/拉丁裔,并且在艾滋病毒诊断时年龄更大,而在三个护理保留效果不佳的轨迹中的人则更年轻。地区贫困指数、农村地区和县级健康排名也与护理轨迹密切相关。如果能够证实与三个护理保留效果不佳的轨迹相关的个体和社区因素是因果关系和可操作的,那么这些因素可以优先考虑,以改善艾滋病毒护理参与度。

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