DNA疫苗加入了对抗新冠病毒的战斗。 - Suppr

DNA vaccines join the fight against COVID-19.

作者信息

Blakney Anna K, Bekker Linda-Gail

机构信息

University of British Columbia, Michael Smith Laboratories, Vancouver, BC V6S0K3, Canada.

The Desmond Tutu HIV Centre, University of Cape Town, Institute of Infectious Disease and Molecular Medicine, Cape Town, South Africa.

出版信息

Lancet. 2022 Apr 2;399(10332):1281-1282. doi: 10.1016/S0140-6736(22)00524-4.

DOI:10.1016/S0140-6736(22)00524-4

PMID:35366995

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8970583/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9796/8970583/3c80a0054415/fx1_lrg.jpg

相似文献

DNA vaccines join the fight against COVID-19.

Lancet. 2022 Apr 2;399(10332):1281-1282. doi: 10.1016/S0140-6736(22)00524-4.

Is there a role for childhood vaccination against COVID-19?

Pediatr Allergy Immunol. 2021 Jan;32(1):9-16. doi: 10.1111/pai.13401. Epub 2020 Nov 20.

Covid-19: From structure to therapeutic targeting in studying approved drugs and local DNA vaccination.

Clin Exp Pharmacol Physiol. 2020 Nov;47(11):1771-1773. doi: 10.1111/1440-1681.13409.

DNA vaccines: a mini review.

Recent Pat DNA Gene Seq. 2011 Aug;5(2):92-6. doi: 10.2174/187221511796392114.

Empowering dentists to administer COVID-19 vaccines.

J Public Health Dent. 2022 Jun;82(3):338-344. doi: 10.1111/jphd.12502. Epub 2022 Jan 19.

Recent advances in therapeutic modalities and vaccines to counter COVID-19/SARS-CoV-2.

Hum Vaccin Immunother. 2020 Dec 1;16(12):3034-3042. doi: 10.1080/21645515.2020.1794685. Epub 2020 Aug 26.

Avian flu: are we prepared to fight against the gathering storm clouds?

J Indian Med Assoc. 2006 Sep;104(9):532.

First COVID-19 DNA vaccine approved, others in hot pursuit.

Nat Biotechnol. 2021 Dec;39(12):1479-1482. doi: 10.1038/d41587-021-00023-5.

SARS-CoV-2 vaccines: fast track versus efficacy.

Lancet Microbe. 2021 Mar;2(3):e89-e90. doi: 10.1016/S2666-5247(21)00034-3. Epub 2021 Feb 9.

India's DNA COVID vaccine is a world first - more are coming.

Nature. 2021 Sep;597(7875):161-162. doi: 10.1038/d41586-021-02385-x.

引用本文的文献

Next-Generation Adenoviral Vector-Based Vaccines for Severe Acute Respiratory Syndrome Coronavirus-2.

Vaccines (Basel). 2025 Apr 14;13(4):406. doi: 10.3390/vaccines13040406.

Skin patch delivery of a SARS-CoV-2 spike DNA vaccine produces broad neutralising antibody responses.

Heliyon. 2025 Feb 7;11(4):e42533. doi: 10.1016/j.heliyon.2025.e42533. eCollection 2025 Feb 28.

Pulmonary Delivery of Nonviral Nucleic Acid-Based Vaccines With Spotlight on Gold Nanoparticles.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2025 Jan-Feb;17(1):e70000. doi: 10.1002/wnan.70000.

New insights for the development of efficient DNA vaccines.

Microb Biotechnol. 2024 Nov;17(11):e70053. doi: 10.1111/1751-7915.70053.

A SARS-CoV-2 RBD vaccine fused to the chemokine MIP-3α elicits sustained murine antibody responses over 12 months and enhanced lung T-cell responses.

Front Immunol. 2024 Feb 2;15:1292059. doi: 10.3389/fimmu.2024.1292059. eCollection 2024.

The quest for nanoparticle-powered vaccines in cancer immunotherapy.

J Nanobiotechnology. 2024 Feb 14;22(1):61. doi: 10.1186/s12951-024-02311-z.

DNA Vaccines: Their Formulations, Engineering and Delivery.

Vaccines (Basel). 2024 Jan 11;12(1):71. doi: 10.3390/vaccines12010071.

Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models.

Nat Commun. 2024 Jan 18;15(1):590. doi: 10.1038/s41467-024-44830-1.

A review of SARS-CoV-2 variants and vaccines: Viral properties, mutations, vaccine efficacy, and safety.

Infect Med (Beijing). 2023 Sep 12;2(4):247-261. doi: 10.1016/j.imj.2023.08.005. eCollection 2023 Dec.

Tracking the COVID-19 vaccines: The global landscape.

Hum Vaccin Immunother. 2023 Dec 31;19(1):2191577. doi: 10.1080/21645515.2023.2191577. Epub 2023 Mar 30.

本文引用的文献

Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D): the interim efficacy results of a phase 3, randomised, double-blind, placebo-controlled study in India.

Lancet. 2022 Apr 2;399(10332):1313-1321. doi: 10.1016/S0140-6736(22)00151-9.

First COVID-19 DNA vaccine approved, others in hot pursuit.

Nat Biotechnol. 2021 Dec;39(12):1479-1482. doi: 10.1038/d41587-021-00023-5.

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.

EClinicalMedicine. 2021 Jan;31:100689. doi: 10.1016/j.eclinm.2020.100689. Epub 2020 Dec 24.

Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.

Lancet Infect Dis. 2019 Sep;19(9):1013-1022. doi: 10.1016/S1473-3099(19)30266-X. Epub 2019 Jul 24.

Engineering DNA vaccines against infectious diseases.

Acta Biomater. 2018 Oct 15;80:31-47. doi: 10.1016/j.actbio.2018.08.033. Epub 2018 Aug 31.

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.

Lancet. 2018 Feb 10;391(10120):552-562. doi: 10.1016/S0140-6736(17)33105-7. Epub 2017 Dec 5.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

DNA vaccines join the fight against COVID-19.

Lancet. 2022 Apr 2;399(10332):1281-1282. doi: 10.1016/S0140-6736(22)00524-4.

Is there a role for childhood vaccination against COVID-19?

Pediatr Allergy Immunol. 2021 Jan;32(1):9-16. doi: 10.1111/pai.13401. Epub 2020 Nov 20.

Covid-19: From structure to therapeutic targeting in studying approved drugs and local DNA vaccination.

Clin Exp Pharmacol Physiol. 2020 Nov;47(11):1771-1773. doi: 10.1111/1440-1681.13409.

DNA vaccines: a mini review.

Recent Pat DNA Gene Seq. 2011 Aug;5(2):92-6. doi: 10.2174/187221511796392114.

Empowering dentists to administer COVID-19 vaccines.

J Public Health Dent. 2022 Jun;82(3):338-344. doi: 10.1111/jphd.12502. Epub 2022 Jan 19.

Recent advances in therapeutic modalities and vaccines to counter COVID-19/SARS-CoV-2.

Hum Vaccin Immunother. 2020 Dec 1;16(12):3034-3042. doi: 10.1080/21645515.2020.1794685. Epub 2020 Aug 26.

Avian flu: are we prepared to fight against the gathering storm clouds?

J Indian Med Assoc. 2006 Sep;104(9):532.

First COVID-19 DNA vaccine approved, others in hot pursuit.

Nat Biotechnol. 2021 Dec;39(12):1479-1482. doi: 10.1038/d41587-021-00023-5.

SARS-CoV-2 vaccines: fast track versus efficacy.

Lancet Microbe. 2021 Mar;2(3):e89-e90. doi: 10.1016/S2666-5247(21)00034-3. Epub 2021 Feb 9.

India's DNA COVID vaccine is a world first - more are coming.

Nature. 2021 Sep;597(7875):161-162. doi: 10.1038/d41586-021-02385-x.

引用本文的文献

Next-Generation Adenoviral Vector-Based Vaccines for Severe Acute Respiratory Syndrome Coronavirus-2.

Vaccines (Basel). 2025 Apr 14;13(4):406. doi: 10.3390/vaccines13040406.

Skin patch delivery of a SARS-CoV-2 spike DNA vaccine produces broad neutralising antibody responses.

Heliyon. 2025 Feb 7;11(4):e42533. doi: 10.1016/j.heliyon.2025.e42533. eCollection 2025 Feb 28.

Pulmonary Delivery of Nonviral Nucleic Acid-Based Vaccines With Spotlight on Gold Nanoparticles.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2025 Jan-Feb;17(1):e70000. doi: 10.1002/wnan.70000.

New insights for the development of efficient DNA vaccines.

Microb Biotechnol. 2024 Nov;17(11):e70053. doi: 10.1111/1751-7915.70053.

A SARS-CoV-2 RBD vaccine fused to the chemokine MIP-3α elicits sustained murine antibody responses over 12 months and enhanced lung T-cell responses.

Front Immunol. 2024 Feb 2;15:1292059. doi: 10.3389/fimmu.2024.1292059. eCollection 2024.

The quest for nanoparticle-powered vaccines in cancer immunotherapy.

J Nanobiotechnology. 2024 Feb 14;22(1):61. doi: 10.1186/s12951-024-02311-z.

DNA Vaccines: Their Formulations, Engineering and Delivery.

Vaccines (Basel). 2024 Jan 11;12(1):71. doi: 10.3390/vaccines12010071.

Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models.

Nat Commun. 2024 Jan 18;15(1):590. doi: 10.1038/s41467-024-44830-1.

A review of SARS-CoV-2 variants and vaccines: Viral properties, mutations, vaccine efficacy, and safety.

Infect Med (Beijing). 2023 Sep 12;2(4):247-261. doi: 10.1016/j.imj.2023.08.005. eCollection 2023 Dec.

Tracking the COVID-19 vaccines: The global landscape.

Hum Vaccin Immunother. 2023 Dec 31;19(1):2191577. doi: 10.1080/21645515.2023.2191577. Epub 2023 Mar 30.

本文引用的文献

Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D): the interim efficacy results of a phase 3, randomised, double-blind, placebo-controlled study in India.

Lancet. 2022 Apr 2;399(10332):1313-1321. doi: 10.1016/S0140-6736(22)00151-9.

First COVID-19 DNA vaccine approved, others in hot pursuit.

Nat Biotechnol. 2021 Dec;39(12):1479-1482. doi: 10.1038/d41587-021-00023-5.

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.

EClinicalMedicine. 2021 Jan;31:100689. doi: 10.1016/j.eclinm.2020.100689. Epub 2020 Dec 24.

Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.

Lancet Infect Dis. 2019 Sep;19(9):1013-1022. doi: 10.1016/S1473-3099(19)30266-X. Epub 2019 Jul 24.

Engineering DNA vaccines against infectious diseases.

Acta Biomater. 2018 Oct 15;80:31-47. doi: 10.1016/j.actbio.2018.08.033. Epub 2018 Aug 31.

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.

Lancet. 2018 Feb 10;391(10120):552-562. doi: 10.1016/S0140-6736(17)33105-7. Epub 2017 Dec 5.

DNA vaccines join the fight against COVID-19.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献