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第三脑室非生殖细胞性生殖细胞瘤的手术切除:二维手术视频。

Surgical Resection of a Third Ventricle Nongerminomatous Germ Cell Tumor: Two-Dimensional Operative Video.

机构信息

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China; National Center for Neurological Disorders, Shanghai, China; Neurosurgical Institute of Fudan University, Shanghai, China; Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, School of Basic Medical Sciences and Institutes of Brain Science, Fudan University, Shanghai, China; Research Unit of New Technologies of Micro-Endoscopy Combination in Skull Base Surgery (2018RU008), Chinese Academy of Medical Sciences, Shanghai, China.

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China; National Center for Neurological Disorders, Shanghai, China; Neurosurgical Institute of Fudan University, Shanghai, China; Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, School of Basic Medical Sciences and Institutes of Brain Science, Fudan University, Shanghai, China; Research Unit of New Technologies of Micro-Endoscopy Combination in Skull Base Surgery (2018RU008), Chinese Academy of Medical Sciences, Shanghai, China; Department of Neurosurgery, Fujian Campus of National Regional Medical Center, Huashan Hospital, Fudan University, Fuzhou, Fujian, China.

出版信息

World Neurosurg. 2022 Jul;163:1. doi: 10.1016/j.wneu.2022.03.103. Epub 2022 Mar 30.

Abstract

Surgical resection of a pineal tumor growing into the third ventricle is difficult owing to the complex neurovascular structures, and nongerminomatous germ cell tumor is the most common malignant tumor in pediatric patients. Removing the tumor efficiently with minimal blood loss while protecting the surrounding neurovascular structure is challenging. We present a surgical case of a 9-year-old patient with a third ventricle nongerminomatous germ cell tumor (Video). Mass effect of the tumor or acute hydrocephalus is the possible reason for the coma. In this case, the reason of coma may be mass effect of the tumor, not the acute hydrocephalus. Informed consent was obtained from the patient's guardian. Intraoperatively we used a modified right head-up park bench position and a linear incision. The right occipital bone flap was designed to cross the superior sagittal sinus and transverse sinus. The primary surgical approach was the occipital transtentorial approach; an alternative was the supracerebellar infratentorial approach. After cutting the tentorium, a spatula was applied to retract the cerebellum and incised tentorium, with no extra brain retraction on the occipital lobe to minimize visual disturbance. The quadrigeminal cistern was opened, and the tumor was yellowish with heterogeneous consistency. Instead of rushing into the tumor debulking, we paid more attention to devascularization of the tumor from bilateral posterior medial choroidal arteries as much as possible. After debulking using an ultrasound aspirator, the tumor was removed in a piecemeal fashion, and the surgical field was inspected using an endoscope for any residue.

摘要

由于复杂的神经血管结构,松果体肿瘤向第三脑室生长的手术切除较为困难,而非精原细胞瘤是小儿患者中最常见的恶性肿瘤。在有效切除肿瘤的同时最大限度地减少出血并保护周围的神经血管结构极具挑战性。我们报告了一例 9 岁患者第三脑室非精原细胞瘤生殖细胞肿瘤的手术病例(视频)。肿瘤的占位效应或急性脑积水可能是导致昏迷的原因。在本例中,昏迷的原因可能是肿瘤的占位效应,而不是急性脑积水。已获得患者监护人的知情同意。术中我们采用改良的右侧头高脚低仰卧位和直线切口。设计右侧枕骨骨瓣以跨越上矢状窦和横窦。主要的手术入路是枕经天幕入路;另一种选择是小脑上蚓部经天幕下入路。切开天幕后,应用解剖刀牵开小脑并切开天幕,枕叶上不进行额外的脑牵拉,以尽量减少视觉干扰。打开四叠体池,肿瘤呈黄色,质地不均匀。我们没有急于进行肿瘤切除术,而是更加注意从双侧后内侧脉络膜动脉尽可能地对肿瘤进行断血。使用超声吸引器切除肿瘤后,将肿瘤分块切除,并使用内镜检查手术野是否有任何残留。

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