Division of Vascular Surgery, Complex Aortic Team, Royal Free NHS Trust, London, UK; Division of Vascular Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.
CHU Nantes, L'Institut du Thorax, Division of Cardiovascular Surgery, Université de Nantes, Nantes, France.
J Vasc Surg. 2022 Sep;76(3):645-655.e3. doi: 10.1016/j.jvs.2022.03.861. Epub 2022 Mar 31.
Real-time aortic deformation during endovascular aortic aneurysm repair (EVAR) has not been reported. Successful EVAR relies on predicting intraoperative aortic-endograft deformation from preoperative imaging. Correct prediction is essential, because malalignment of endografts decreases patient survival. We describe intraoperative aortic deformation during infrarenal EVAR and complex fenestrated/branched EVAR (F/BEVAR), relating deformation to preoperative anatomy and follow-up outcomes.
A multicenter, retrospective cohort of aortic aneurysm patients undergoing operation between January 2019 and February 2021, substratified by repair, infrarenal EVAR (n = 50), F/BEVAR (n = 80), and iliac branch graft with F/B/EVAR (IBG + F/B/EVAR; n = 27), were compared using software-based nonrigid two- and three-dimensional aortic deformational intraoperative assessment (CYDAR). Preoperative computed tomography reconstructions of aortic and iliac tortuosities were assessed against intraoperative deformation, the primary outcome, and related to perioperative and follow-up adverse outcomes.
All treatment groups had low preoperative visceral aortic tortuosity; the EVAR group had higher iliac tortuosity (1.43 ± 0.05; P = .018). Intraoperative aortic visceral deformation was consistently cranial and anterior; IBG + F/B/EVAR patients had the largest magnitude deformation (superior mesenteric artery, EVAR 5.1 ± 0.9 mm; F/BEVAR 4.4 ± 0.4 mm; IBG 8.3 ± 1.2 mm; P = .004). Celiac artery, superior mesenteric artery, and bilateral renal artery deformations were correlated (R = 0.923-0.983). Iliac deformation was variable in magnitude and direction. Preoperative tortuosity was not correlated with the magnitude of intraoperative deformation nor was deformation magnitude related to endograft instability during follow-up, including endoleak development, reinterventions, or visceral vessel complications.
The aorta deforms consistently during EVAR at the visceral aortic segment but unpredictably at the iliac bifurcation. Aortoiliac deformation is unrelated to adverse perioperative outcomes, branch instability, or reinterventions during short-term follow-up.
血管内主动脉瘤修复术(EVAR)过程中的实时主动脉变形尚未有报道。成功的 EVAR 依赖于从术前影像学预测术中主动脉-移植物的变形。正确的预测至关重要,因为移植物的不对中会降低患者的生存率。我们描述了肾下 EVAR 和复杂开窗/分支 EVAR(F/BEVAR)期间的术中主动脉变形,将变形与术前解剖结构和随访结果联系起来。
对 2019 年 1 月至 2021 年 2 月期间接受手术的主动脉瘤患者进行了多中心回顾性队列研究,根据修复方式进行分层,分为肾下 EVAR(n=50)、F/BEVAR(n=80)和髂分支移植物加 F/BEVAR(IBG+F/BEVAR;n=27)。使用基于软件的非刚性二维和三维主动脉变形术中评估(CYDAR)比较各组。术中主动脉和髂动脉扭曲的术前计算机断层扫描重建与主要结果进行了对比,并与围手术期和随访不良结果相关联。
所有治疗组的内脏主动脉术前扭曲度均较低;EVAR 组的髂动脉扭曲度较高(1.43±0.05;P=.018)。术中主动脉内脏变形始终向头侧和前侧;IBG+F/BEVAR 患者的变形幅度最大(肠系膜上动脉,EVAR 5.1±0.9mm;F/BEVAR 4.4±0.4mm;IBG 8.3±1.2mm;P=.004)。腹腔动脉、肠系膜上动脉和双侧肾动脉的变形呈正相关(R=0.923-0.983)。髂动脉的变形幅度和方向均存在差异。术前扭曲度与术中变形幅度无相关性,变形幅度与随访期间移植物的不稳定性也无相关性,包括内漏的发展、再次干预或内脏血管并发症。
EVAR 过程中主动脉在内脏主动脉段始终变形,但在髂动脉分叉处变形不可预测。腹主动脉和髂动脉的变形与不良的围手术期结果、分支不稳定或短期随访期间的再次干预无关。