Zhang Yi, Yuan Zhi-Liang, Deng Xin-Yu, Wei Hao-Dong, Wang Wen-Long, Xu Zhenghua, Feng Yongwei, Shi Xueli
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Food Chem. 2022 Aug 30;386:132753. doi: 10.1016/j.foodchem.2022.132753. Epub 2022 Mar 21.
The residues of bisphenol A (BPA) in milk packaging may transfer to milk, adversely affecting the human endocrine system. Consequently, to analyse or monitor BPA, it is imperative to develop rapid and effective approaches to BPA extraction from milk and milk packing as BPA is usually present in trace levels. Herein, we developed a rapid, simple, and low-cost dispersive-membrane-solid-phase-extraction (DME) for BPA with MIL-101(Cr) mixed-matrix-membrane (MMM). The MMM had large surface area (1322.09 m/g) and pore volume (0.65 cm/g), possessed great extraction efficiency of BPA, and kept more than 90% extraction efficiency after 20 times of reuse. Using the developed MIL-101(Cr)-MMM-based DME coupled with HPLC-fluorescence detector, we received an adequate linearity in the range of 0.1 ∼ 50 μg/L BPA and a limit of detection as low as 16 ng/L under optimized conditions. The recoveries of BPA in milk and milk bottles were from 74.2% to 110.6%, with RSDs less than 9.4%.
牛奶包装中的双酚A（BPA）残留可能会转移到牛奶中，对人体内分泌系统产生不利影响。因此，为了分析或监测双酚A，由于双酚A通常以痕量水平存在，开发从牛奶和牛奶包装中快速有效地提取双酚A的方法势在必行。在此，我们开发了一种使用MIL-101（Cr）混合基质膜（MMM）的快速、简单且低成本的双酚A分散膜固相萃取（DME）方法。该MMM具有大表面积（1322.09 m/g）和孔体积（0.65 cm/g），对双酚A具有很高的萃取效率，并且在重复使用20次后仍保持超过90%的萃取效率。使用所开发的基于MIL-101（Cr）-MMM的DME与高效液相色谱-荧光检测器联用，在优化条件下，我们在0.1 ∼ 50 μg/L双酚A范围内获得了良好的线性，检测限低至16 ng/L。牛奶和奶瓶中双酚A的回收率为74.2%至110.6%，相对标准偏差小于9.4%。
