Jiangsu Key Laboratory of Advanced Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, China.
Bioelectrochemistry. 2022 Aug;146:108110. doi: 10.1016/j.bioelechem.2022.108110. Epub 2022 Mar 28.
To introduce abundant carboxyl (COOH) groups to the surface of multi-walled carbon nanotubes (MWCNTs) while maintaining the pristine structure of MWCNTs, 3,4,9,10-perylene tetracarboxylic acid (PTCA) was non-covalently grafted to the sidewalls of MWCNTs. The obtained PTCA functionalized MWCNTs (MWCNTs-PTCA) functioned as a scaffold for the further introduction of chitosan (CS) via electrostatic attractions and hydrogen-bonds. The resultant CS/MWCNTs-PTCA could be used for electrochemical chiral sensing of tryptophan (Trp) enantiomers due to the intrinsic chirality of CS and the high electrocatalytic activity of MWCNTs. Under optimized conditions, the Trp enantiomers could be effectively discriminated at the CS/MWCNTs-PTCA modified electrode by differential pulse voltammetry (DPV), demonstrating that the developed CS/MWCNTs-PTCA might be a potential candidate for the construction of electrochemical chiral sensors.
为了在保持多壁碳纳米管（MWCNTs）原始结构的同时向其表面引入丰富的羧基（COOH）基团，将 3,4,9,10-苝四羧酸（PTCA）非共价接枝到 MWCNTs 的侧壁上。所得的 PTCA 功能化 MWCNTs（MWCNTs-PTCA）通过静电吸引和氢键作用作为壳聚糖（CS）进一步引入的支架。由于 CS 的固有手性和 MWCNTs 的高电催化活性，所得的 CS/MWCNTs-PTCA 可用于色氨酸（Trp）对映体的电化学手性传感。在优化条件下，通过差分脉冲伏安法（DPV）可在 CS/MWCNTs-PTCA 修饰电极上有效区分 Trp 对映体，表明所开发的 CS/MWCNTs-PTCA 可能是构建电化学手性传感器的潜在候选物。
