Department of Stomatology II, Faculty of Medicine and Nursery University of the Basque Country (EHU) Barrio Sarriena s/n, 48940. Leioa. Vizcaya. Spain
Med Oral Patol Oral Cir Bucal. 2022 Sep 1;27(5):e419-e425. doi: 10.4317/medoral.25348.
Parkinson's disease (PD) is one of the leading neurological disorders, affecting more than 6 million people worldwide. These patients present motor and non-motor symptoms, including oral pathology. The objective of this research is to determine the oral health of patients diagnosed with PD, in order to stablish a specific preventive oral health programme.
Case-control study on 104 PD and 106 control patients. The pre-designed clinical protocol included a complete oral examination on general aspects, standardised epidemiological index for caries, periodontal disease and edentulism, analysis of oral hygiene, presence of mucous/ salivary/ functional disorder, and dental treatments.
A higher number of PD patients consumed daily sweets (p<0.004) and antidepressant drugs (p<0.004). Patients with PD practised less interdental hygiene (p<0.023). The mean plaque index was higher in PD (p<0.003). Drooling (p<0.001), xerostomia (p<0.001), hyposialia (p<0.001), dysphagia (p<0.001), hypogeusia/dysgeusia (p<0.025) and chewing difficulty (p<0.006) were more common in PD.
Oral disorders are frequent in PD. A good knowledge of these alterations will allow us design a specific preventive protocol. Some oral alterations may be a sign of diagnostic alert or progression of PD.
帕金森病(PD)是一种主要的神经退行性疾病,影响全球超过 600 万人。这些患者表现出运动和非运动症状,包括口腔病理学。本研究旨在确定被诊断为 PD 的患者的口腔健康状况,以便制定具体的预防性口腔健康计划。
对 104 名 PD 患者和 106 名对照患者进行病例对照研究。预先设计的临床方案包括对一般方面进行全面口腔检查、龋病、牙周病和无牙颌的标准化流行病学指数、口腔卫生分析、存在黏膜/唾液/功能障碍以及牙科治疗。
更多的 PD 患者每天食用甜食(p<0.004)和抗抑郁药(p<0.004)。PD 患者进行的牙间清洁较少(p<0.023)。PD 患者的菌斑指数较高(p<0.003)。流涎(p<0.001)、口干(p<0.001)、唾液分泌减少(p<0.001)、吞咽困难(p<0.001)、味觉减退/味觉障碍(p<0.025)和咀嚼困难(p<0.006)在 PD 中更为常见。
口腔疾病在 PD 中很常见。对这些改变的充分了解将使我们能够设计一个特定的预防方案。一些口腔改变可能是 PD 诊断警示或进展的迹象。