Lee Kevin, Rahimi Osman, Gupta Neelesh, Ahsan Chowdhury
Department of Internal Medicine, University of Nevada, Las Vegas, 1707 W Charleston Blvd, Suite 100, Las Vegas, NV 89102, USA.
Department of Cardiology, University of Nevada, Las Vegas, 1800 W Charleston Blvd, Las Vegas, NV 89102, USA.
Case Rep Cardiol. 2022 Mar 30;2022:9371818. doi: 10.1155/2022/9371818. eCollection 2022.
. Coronavirus 2019 (COVID-19) was initially identified approximately in December 2019 at Wuhan, China, as patients presented with vague prodromal and respiratory symptoms. With the developing investigation of its clinical manifestation, cardiac symptoms have been widely reported including acute coronary syndromes, myocarditis, arrhythmias, heart failure, and cardiac arrest. . An 84 year-old male with history of coronary artery disease, hypertension, and hyperlipidemia presented to an outside urgent care with prodromal symptoms. The patient had received the second Pfizer vaccine three months prior. This presentation, he was found to be COVID-19 positive as well as bradycardic with a complete AV block. He was transferred to a tertiary center for further evaluation and management. However, after transfer, the patient refused further invasive cardiac interventions and after medical therapy was discharged home in complete AV block. . We report a novel case of a Pfizer-vaccinated patient whose initial presenting symptoms of COVID-19 included a complete AV block as well as the challenges and difficulties in approaching such patients. Although this patient's etiology of his complete AV block may result from multiple factors, given the acuity in setting of concurrent COVID-19 infections, top differentials include viral myocarditis, COVID-19-induced Takotsubo cardiomyopathy complicated by a complete AV-block, or a direct conduction pathway infection. Management of patients should focus on a multidisciplinary approach, and prevention is critical via vaccination.
2019年冠状病毒病(COVID-19)最初于2019年12月左右在中国武汉被发现,当时患者出现模糊的前驱症状和呼吸道症状。随着对其临床表现研究的深入,心脏症状被广泛报道,包括急性冠状动脉综合征、心肌炎、心律失常、心力衰竭和心脏骤停。一名84岁男性,有冠状动脉疾病、高血压和高脂血症病史,因前驱症状前往外部紧急护理机构就诊。该患者三个月前接种了第二剂辉瑞疫苗。此次就诊时,发现他COVID-19检测呈阳性,且心动过缓并伴有完全性房室传导阻滞。他被转至三级中心进行进一步评估和治疗。然而,转院后,患者拒绝进一步的侵入性心脏干预,经药物治疗后,以完全性房室传导阻滞状态出院回家。我们报告了一例接种辉瑞疫苗的患者的新病例,其COVID-19的初始表现症状包括完全性房室传导阻滞,以及处理此类患者时面临的挑战和困难。尽管该患者完全性房室传导阻滞的病因可能由多种因素导致,但鉴于同时合并COVID-19感染的紧迫性,主要鉴别诊断包括病毒性心肌炎、COVID-19诱发的应激性心肌病并发完全性房室传导阻滞,或直接的传导通路感染。对患者的管理应侧重于多学科方法,并且通过接种疫苗进行预防至关重要。