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一例严重的牙源性感染合并前胸壁及颈部坏死性筋膜炎

A Severe Case of Odontogenic Infection and Necrotizing Fasciitis of the Anterior Chest Wall and Neck.

作者信息

Huff Mallorie L, Wilson Kyle S, Kane Kathleen E, Wheel Kathryn L, Stirparo Joseph J

机构信息

Department of Surgery, Division of Trauma and Acute Care Surgery, University of South Florida Morsani College of Medicine/Lehigh Valley Health Network Campus, Bethlehem, USA.

Department of Emergency and Hospital Medicine, University of South Florida Morsani College of Medicine/Lehigh Valley Health Network Campus, Bethlehem, USA.

出版信息

Cureus. 2022 Feb 21;14(2):e22438. doi: 10.7759/cureus.22438. eCollection 2022 Feb.

DOI:10.7759/cureus.22438
PMID:35371740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8942170/
Abstract

Necrotizing fasciitis is a life-threatening infection that can be rapidly fatal. Early identification and emergent surgical management are essential to minimize morbidity and mortality. This case report describes a 25-year-old male who presented to the emergency department with a three-day history of worsening left lower dental infection and new-onset neck pain and swelling. He received broad-spectrum antibiotics and intravenous fluid resuscitation and underwent computed tomography of the neck and chest. Following intensive care unit admission, he underwent tooth extraction where intraoperative evaluation revealed subcutaneous crepitus. Immediate debridement was performed, revealing copious foul-smelling purulent discharge and necrotic tissue extending over the anterior chest wall and neck. During his hospital course, he underwent multiple debridements to manage the expanding infection. The final tissue defect was substantial, with deep dissection to muscle extending over the entire anterior surface of the rib cage to just inferior to the clavicles. This significant tissue defect was managed with skin grafts, and he was discharged home in stable condition. The patient is doing well almost a year after discharge. The key to our patient's survival was the early identification and debridement of the affected tissue. Our study reinforces the tenants of wound care and aggressive management required to bolster patient odds of survival in the setting of necrotizing fasciitis and underscores the importance of maintaining vigilance in patients presenting with dental infections. This study is unique in that our patient was young, with a past medical history significant for polydrug use, and the area of debridement was substantial.

摘要

坏死性筋膜炎是一种危及生命的感染,可迅速致命。早期识别和紧急手术处理对于将发病率和死亡率降至最低至关重要。本病例报告描述了一名25岁男性,他因左下牙感染加重伴新发颈部疼痛和肿胀3天就诊于急诊科。他接受了广谱抗生素治疗和静脉补液复苏,并进行了颈部和胸部的计算机断层扫描。入住重症监护病房后,他接受了拔牙手术,术中评估发现皮下气肿。立即进行了清创,发现有大量恶臭脓性分泌物和坏死组织,延伸至前胸壁和颈部。在住院期间,他接受了多次清创以控制不断扩大的感染。最终的组织缺损很大,深部解剖至肌肉,延伸至整个胸廓前表面直至锁骨下方。通过植皮处理了这一严重的组织缺损,他出院时情况稳定。出院近一年后,患者情况良好。我们患者存活的关键是早期识别并清创受影响的组织。我们的研究强化了伤口护理的原则以及在坏死性筋膜炎情况下提高患者生存几率所需的积极处理,并强调了对有牙感染的患者保持警惕的重要性。本研究的独特之处在于我们的患者很年轻,有大量使用多种药物的病史,且清创面积很大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/3de66c0a5e24/cureus-0014-00000022438-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/bf95715104db/cureus-0014-00000022438-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/196f3b97722e/cureus-0014-00000022438-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/3de66c0a5e24/cureus-0014-00000022438-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/bf95715104db/cureus-0014-00000022438-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/196f3b97722e/cureus-0014-00000022438-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7209/8942170/3de66c0a5e24/cureus-0014-00000022438-i03.jpg

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本文引用的文献

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Odontogenic necrotizing fasciitis: a systematic review of the literature.牙源性坏死性筋膜炎:文献系统综述
BMC Ear Nose Throat Disord. 2018 Aug 15;18:14. doi: 10.1186/s12901-018-0059-y. eCollection 2018.
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Cervical necrotizing fasciitis: Systematic review and analysis of 1235 reported cases from the literature.宫颈坏死性筋膜炎:文献报道的 1235 例病例的系统回顾和分析。
Head Neck. 2018 Sep;40(9):2094-2102. doi: 10.1002/hed.25184. Epub 2018 Jun 22.
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Mortality of necrotizing fasciitis: relative influence of individual and hospital-level factors, a nationwide multilevel study, France, 2007-12.
坏死性筋膜炎的死亡率:个体和医院水平因素的相对影响,一项全国性的多水平研究,法国,2007-2012 年。
Br J Dermatol. 2017 Dec;177(6):1575-1582. doi: 10.1111/bjd.15615. Epub 2017 Oct 9.
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An Unusual Presentation of Ludwig's Angina Complicated by Cervical Necrotizing Fasciitis: A Case Report and Review of the Literature.路德维希咽峡炎并发颈部坏死性筋膜炎的罕见表现:病例报告及文献综述
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Cervical necrotizing fasciitis caused by dental infection: A review and case report.牙源性感染引起的颈部坏死性筋膜炎:综述与病例报告
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Craniocervical necrotizing fasciitis with and without thoracic extension: management strategies and outcome.伴或不伴胸段扩展的颅颈坏死性筋膜炎:治疗策略与结果
Am J Otolaryngol. 2009 Jan-Feb;30(1):17-23. doi: 10.1016/j.amjoto.2007.12.007. Epub 2008 Jul 10.
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Craniocervical necrotizing fasciitis: an 11-year experience.颅颈坏死性筋膜炎:11年经验总结
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