SPRINT 研究中 CKD 患者的肾小管生物标志物与脑成像的关系。
The Relationship of Kidney Tubule Biomarkers with Brain Imaging in CKD Patients in SPRINT.
机构信息
Division of Nephrology-Hypertension, University of California San Diego, San Diego, California.
Department of Medicine-Nephrology, Stanford University, Palo Alto, California.
出版信息
Kidney360. 2021 Dec 8;3(2):337-340. doi: 10.34067/KID.0007702021. eCollection 2022 Feb 24.
Abstract
Urine biomarker concentrations reflecting kidney tubule injury and dysfunction were not associated with brain MRI measures.Higher eGFR was associated with lower total brain cerebral blood flow.This is the first evaluation of the relationship of kidney tubule biomarkers with brain imaging by MRI in patients with CKD.
摘要
尿液生物标志物浓度反映了肾小管损伤和功能障碍，但与脑 MRI 测量结果无关。较高的 eGFR 与总脑脑血流量较低相关。这是首次对 CKD 患者的肾脏管生物标志物与 MRI 脑成像之间的关系进行评估。
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