Peng Jintao, Guo Jiayi, Zeng Zhi, Liang Xiaoyan, Zeng Haitao, Li Manchao
Reproductive Medicine Research Center, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Int J Gynaecol Obstet. 2022 Nov;159(2):563-567. doi: 10.1002/ijgo.14207. Epub 2022 Apr 29.
To assess the prevalence of chronic endometritis (CE) among infertile women with endometrial polyps (EP).
From June 2017 to October 2021, 583 patients in the polyp group (group A-group A1: single-polyp group, 322 patients; group A2: multiple-polyp group, 261 patients) and 4534 patients in the non-polyp group (group B) were included in this retrospective study. Hysteroscopic polypectomy was performed in group A. Endometrial biopsy and CD138 immunohistochemistry staining for specimens was carried out in all groups.
Prevalence of CE was significantly higher in group A than in group B (45.28% vs. 27.94%, P < 0.001). A significantly higher prevalence of CE was found in group A1 and group A2 compared with group B (42.24% vs. 27.94%, P < 0.001; 49.04% vs. 27.94%, P < 0.001; respectively). No significant difference in the comparison of CE prevalence was found between group A1 and group A2. Similar results were achieved in the subgroup analysis among patients aged 40 years or older and patients younger than 40 years.
EP, either single EP or multiple EP, positively correlates with CE. The prevalence of CE was similar between the single-polyp group and the multiple-polyp group.
评估子宫内膜息肉（EP）不孕女性中慢性子宫内膜炎（CE）的患病率。
本回顾性研究纳入了2017年6月至2021年10月息肉组的583例患者（A组：A1组为单发性息肉组，322例患者；A2组为多发性息肉组，261例患者）和非息肉组的4534例患者（B组）。A组进行了宫腔镜息肉切除术。所有组均对标本进行了子宫内膜活检及CD138免疫组化染色。
A组CE患病率显著高于B组（45.28% 对27.94%，P < 0.001）。与B组相比，A1组和A2组CE患病率显著更高（分别为42.24% 对27.94%，P < 0.001；49.04% 对27.94%，P < 0.001）。A1组和A2组CE患病率比较无显著差异。40岁及以上患者和40岁以下患者的亚组分析也得到了类似结果。
EP，无论是单发性EP还是多发性EP，均与CE呈正相关。单发性息肉组和多发性息肉组CE患病率相似。
