Ramírez Purificación, Otero Remedios, Barberà Joan Albert
Servicio de Neumología, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, Spain.
Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Hospital Universitario Virgen del Rocío-Instituto de Biomedicina de Sevilla (IBiS); CSIC; Universidad de Sevilla, Sevilla, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
Arch Bronconeumol. 2020 May;56(5):314-321. doi: 10.1016/j.arbr.2020.03.007. Epub 2020 Apr 21.
Persistent thrombotic lesions are common in patients with pulmonary embolism. These lesions occur on a clinical spectrum, ranging from an asymptomatic course with complete functional recovery to chronic thromboembolic pulmonary hypertension. The concept of chronic thromboembolic disease has emerged in recent years to describe a subgroup of patients with persistent thrombotic lesions who have symptoms on exertion and pulmonary vascular dysfunction, but no pulmonary hypertension at rest. The prevalence of this entity is unknown and the criteria for diagnosing it are not defined. The aim of this article is to analyze post-pulmonary embolism sequelae and review existing evidence on chronic thromboembolic disease, with special emphasis on its diagnosis and therapeutic approach.
持续性血栓性病变在肺栓塞患者中很常见。这些病变呈临床谱状，范围从功能完全恢复的无症状病程到慢性血栓栓塞性肺动脉高压。近年来出现了慢性血栓栓塞性疾病的概念，用于描述一组有持续性血栓性病变、运动时出现症状且存在肺血管功能障碍但静息时无肺动脉高压的患者。该疾病实体的患病率尚不清楚，诊断标准也未明确。本文旨在分析肺栓塞后遗症，并综述关于慢性血栓栓塞性疾病的现有证据，特别强调其诊断和治疗方法。
