Khalfen E Sh, Ivanova I A
Kardiologiia. 1986 Sep;26(9):66-70.
Daily 500 mg doses of aspirin were shown to be sufficient to produce lasting (one year long) inhibition of platelet aggregation. Two matched samples of postmyocardial infarction patients were compared: 844 untreated controls and 570 patients treated with 500 mg aspirin daily for 1 year following myocardial infarction. In the treated sample, the incidence of recurrent myocardial infarction, including sudden death, dropped from 13.1 to 8.9%, coronary mortality, including sudden death, from 7.2 to 4.7%, sudden death rate, from 3.2 to 1.9%, and total mortality, from 9.3 to 6.6%, as compared to the untreated sample.
每日服用500毫克阿司匹林已被证明足以产生持久（长达一年）的血小板聚集抑制作用。对两组心肌梗死后患者的配对样本进行了比较：844名未接受治疗的对照组患者和570名心肌梗死后每天服用500毫克阿司匹林，持续1年的患者。与未治疗的样本相比，在接受治疗的样本中，复发性心肌梗死（包括猝死）的发生率从13.1%降至8.9%，冠状动脉死亡率（包括猝死）从7.2%降至4.7%，猝死率从3.2%降至1.9%，总死亡率从9.3%降至6.6%。
