Caliskan Kader, Can Gulbeyaz
Anadolu Medical Center, Cumhuriyet Mahallesi, 2255 Sokak, No: 3 Gebze, 41400, Kocaeli, Turkey.
Istanbul University - Cerrahpasa Florence Nightingale Nursing Faculty, Abide-i Hürriyet Cad, Caglayan 34403, Istanbul, Turkey.
Support Care Cancer. 2022 Jul;30(7):5881-5890. doi: 10.1007/s00520-022-07017-2. Epub 2022 Apr 4.
This descriptive study was conducted to determine symptoms experienced at home in the early period by patients who received hematopoietic stem cell transplantation (HSCT), identify coping behaviors used by the patients in the management of symptoms and assess the quality of life of these patients.
The study included 200 patients who had received HSCT at a private hospital in Kocaeli in Turkey between October 2017 and November 2018 and been discharged. The data of the study were collected by using a patient information and interview form developed by the researcher, the Memorial Symptom Assessment Scale and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30.
The mean age of the patients was approximately 51, 39% (n = 78) of the patients were female, 61% (n = 122) were male, and the vast majority (82%) were married. The three most frequently experienced symptoms among the patients after being discharged were identified as pain (63%), weakness (48%), and loss of appetite (43%). It was found that the vast majority of the patients complied with coping behaviors reported in the literature, but these behaviors were partially effective. Clinical diagnosis, type of transplant, status of re-hospitalization of the being discharged, and number of problems experienced were identified as variables that were significantly effective on the treatment-related symptom experiences and many dimensions of the quality of life of the patients (p < 0.05).
It was determined that the patients who were included in this study experienced various symptoms on different levels and at different frequencies. Regarding the effectiveness of the approaches used by the patients in coping with the symptoms they experienced, it was determined that the approaches they used to cope with nausea-vomiting, fever and insomnia were effective, and those they used for weight loss and anxiety were ineffective.
本描述性研究旨在确定接受造血干细胞移植（HSCT）的患者在早期在家中所经历的症状，识别患者在症状管理中所采用的应对行为，并评估这些患者的生活质量。
该研究纳入了200例于2017年10月至2018年11月期间在土耳其科贾埃利一家私立医院接受HSCT并已出院的患者。研究数据通过使用研究者编制的患者信息及访谈表、纪念症状评估量表和欧洲癌症研究与治疗组织生活质量问卷核心30项来收集。
患者的平均年龄约为51岁，39%（n = 78）的患者为女性，61%（n = 122）为男性，绝大多数（82%）已婚。出院后患者中最常经历的三种症状被确定为疼痛（63%）、虚弱（48%）和食欲不振（43%）。发现绝大多数患者遵循了文献中报道的应对行为，但这些行为部分有效。临床诊断、移植类型、出院后再次住院情况以及所经历问题的数量被确定为对患者与治疗相关的症状体验和生活质量的多个维度有显著影响的变量（p < 0.05）。
确定本研究纳入的患者在不同程度和不同频率上经历了各种症状。关于患者用于应对所经历症状的方法的有效性，确定他们用于应对恶心呕吐、发热和失眠的方法有效，而用于应对体重减轻和焦虑的方法无效。
