Dykstra D D, Reid W M
Poult Sci. 1978 Jan;57(1):85-9. doi: 10.3382/ps.0570085.
Bacteria-free, monofloral, and conventional chicks were infected with Eimeria tenella. Monofloral chicks were established by inoculating birds in several gnotobiotic isolators with a single species of Escherichia coli or with one of three Bacteroides sp. isolates (No. 157, No. 202, or No. 366). Daily weights of individual birds were recorded for six days post-infection (PI). On Day 6 PI all birds were sacrificed and cecal lesions were scored. Conventional, infected birds lost weight on days 5 and 6 PI and showed severe lesions. Birds maintained as monofloral groups with isolates of Bacteroides sp. No. 157, No. 202 or E. coli showed equally severe lesions, but lost weight only on day 6 PI. Conventional, uninfected birds with no lesions, birds infected with Bacteroides sp. isolate No. 366 with mild lesions, and bacteria-free birds with mild to severe coccidial lesions all continued to gain weight on each day post-infection.
无菌、单菌丛和常规雏鸡感染了柔嫩艾美耳球虫。单菌丛雏鸡是通过在几个悉生隔离器中给鸟类接种单一的大肠杆菌菌株或三种拟杆菌属菌株（第157号、第202号或第366号）之一而建立的。在感染后六天（PI）记录每只鸟的每日体重。在感染后第6天，所有鸟都被处死，并对盲肠病变进行评分。常规感染的鸟在感染后第5天和第6天体重减轻，并表现出严重病变。用第157号、第202号拟杆菌属菌株或大肠杆菌作为单菌丛组饲养的鸟表现出同样严重的病变，但仅在感染后第6天体重减轻。常规未感染且无病变的鸟、感染第366号拟杆菌属菌株且病变较轻的鸟以及无菌且有轻度至重度球虫病病变的鸟在感染后的每一天体重都继续增加。
