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最新高血压研究为亚洲临床实践提供信息。

Latest hypertension research to inform clinical practice in Asia.

机构信息

Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.

Department of Pharmacology, Ehime University, Graduate School of Medicine, Ehime, Japan.

出版信息

Hypertens Res. 2022 Apr;45(4):555-572. doi: 10.1038/s41440-022-00874-8. Epub 2022 Apr 5.

DOI:10.1038/s41440-022-00874-8
PMID:35379955
Abstract

Despite the challenges associated with the coronavirus pandemic, the last 2 years have been active periods for hypertension research and initiatives in Asia. There are new hypertension guidelines from the World Health Organization that can be interpreted and applied locally. This is also the case for data from the latest Blood Pressure Lowering Treatment Trialists' Collaboration meta-analysis, which showed that greater reductions in systolic blood pressure (BP) are associated with lower risks of cardiovascular events. The randomized controlled Strategy of Blood Pressure Intervention in the Elderly Hypertensive study and the Salt Substitute and Stroke Study provide local data to inform practice. Other initiatives to help reduce high salt intake in Asia are also underway. Both drug-resistant and nocturnal hypertension are appropriate areas of focus in Asia, and there are an increasing number of pharmacological and non-pharmacological treatment options for these conditions. Digital therapeutics to promote uptake and implementation of lifestyle interventions are showing promise, and other digital-based strategies such as telemedicine, wearable BP monitors to detect beat-by-beat BP and artificial intelligence will no doubt become integral parts of future strategies to reduce the burden of hypertension and hypertension-related disease. A number of initiatives from the Hypertension Cardiovascular Outcome Prevention and Evidence in Asia Network and Japanese Society of hypertension are underway, and there is good reason for optimism regarding the ongoing and future management of hypertension in Asia based on these and the active research activities in the region.

摘要

尽管与冠状病毒大流行相关的挑战,但过去两年是亚洲高血压研究和计划的活跃时期。世界卫生组织有新的高血压指南,可以在当地进行解释和应用。最新的降压治疗试验者协作荟萃分析数据也是如此,该分析表明收缩压(BP)降低幅度越大,心血管事件的风险越低。随机对照老年高血压血压干预策略研究和盐替代品与中风研究提供了当地数据,为实践提供信息。亚洲还在开展其他减少高盐摄入的计划。耐药性高血压和夜间高血压都是亚洲的重点关注领域,针对这些疾病的药物和非药物治疗选择也越来越多。促进生活方式干预措施的采用和实施的数字治疗方法显示出了希望,其他基于数字的策略,如远程医疗、用于检测实时血压的可穿戴血压监测仪和人工智能,无疑将成为未来降低高血压及其相关疾病负担的策略的重要组成部分。亚洲高血压心血管结局预防和证据网络和日本高血压学会正在开展多项计划,基于这些计划和该地区的积极研究活动,亚洲高血压的当前和未来管理有充分的理由保持乐观。

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Hypertens Res. 2023 Dec;46(12):2557-2560. doi: 10.1038/s41440-023-01471-z. Epub 2023 Dec 5.
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