Department of Oncology Chemotherapy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
J Cancer Res Ther. 2021 Dec;17(7):1651-1655. doi: 10.4103/jcrt.JCRT_1353_21.
The objective of the study is to investigate the effect of the reverse-tapered peripherally inserted central catheters (PICC) and the nontapered PICC in tumor chemotherapy.
Retrospective January to May 2019, 110 subjects were collected in the study, including a group of 49 patients with the reverse-tapered PICC catheters. In the other group, 61 patients were implanted with the nontapered PICC catheters. The incidence of PICC catheter-related symptomatic thrombosis, the difficulty degree of catheterization, and the rate of bleeding at the puncture point 24 h after catheterization were compared between two groups.
The comparison of the difficulty of catheterization and the permeability rate at puncture point 24 h after catheterization between the two groups showed statistically significant differences (all P < 0.05). There was no significant difference in the incidence of symptomatic thrombosis associated with PICC catheters between the two groups (P > 0.05).
The reverse-tapered PICC and the nontapered PICC catheters have similar safety performance in tumor chemotherapy; different design types of PICC were selected according to the treatment needs of patients.
本研究旨在探讨反向锥形和非锥形经外周静脉置入中心静脉导管（PICC）在肿瘤化疗中的应用效果。
回顾性分析 2019 年 1 月至 5 月期间的 110 例患者，其中 49 例患者使用反向锥形 PICC 导管，61 例患者使用非锥形 PICC 导管。比较两组患者 PICC 导管相关性症状性血栓形成的发生率、置管难度和置管后 24 小时穿刺点出血率。
两组患者置管难度和置管后 24 小时穿刺点出血率比较，差异均有统计学意义（均 P<0.05）；两组患者 PICC 导管相关性症状性血栓形成的发生率比较，差异无统计学意义（P>0.05）。
反向锥形和非锥形 PICC 导管在肿瘤化疗中具有相似的安全性；应根据患者的治疗需求选择不同设计类型的 PICC。
