Bi Andrew S, Shankar Dhruv S, Vasavada Kinjal D, Fisher Nina D, Strauss Eric J, Alaia Michael J, Campbell Kirk A
Division of Sports Medicine, NYU Langone Orthopedic Hospital, 333 East 38th Street 4th Floor, New York, NY, 10016, USA.
NYU Langone Orthopedic Hospital, 301 E 17th St, New York, NY, 10003, USA.
Knee Surg Relat Res. 2022 Apr 5;34(1):19. doi: 10.1186/s43019-022-00147-1.
Patient-reported allergies (PRAs) are often stigmatized as a potential nonmodifiable risk factor for increased pain and worse functional outcomes following surgery. However, there is a dearth of literature directly assessing the impact of PRAs on outcomes in sport surgeries such as medial patellofemoral ligament reconstruction (MPFLR). The purpose of our study was to determine whether PRAs were associated with worse outcomes following MPFLR.
We conducted a retrospective review of patients who underwent MPFLR at our institution from 2011 to 2019. Patients were included if they had at least 12 months of follow-up. PRAs were obtained from preoperative medical assessments and categorized by drug class. Demographic and perioperative data were obtained from electronic medical records. Postoperative outcomes were measured using a telephone survey and included recurrent instability, Visual analog scale (VAS) for pain, VAS for sports, Kujala score, MPFL-Return to Sport after Injury (MPFL-RSI) score, and overall satisfaction score. Multiple linear regression was used to determine association between PRAs and outcome measures, and p-values less than 0.05 were considered significant.
The cohort included 141 MPFLR. Most patients were female (98, 70%) with an average age of 25 years (range 12-56 years). Average follow-up time was 47 months. Forty-seven patients (33%) reported at least one PRA. There were no significant differences in postoperative pain, functional outcomes, satisfaction, or return to sport between patients with or without PRAs (all p > 0.05). Absence of antibiotic PRAs was predictive of higher VAS (p < 0.007), but there were no other differences. There were no significant differences in outcomes between patients without PRAs, PRAs without a concomitant psychiatric disorder, or PRAs with a concomitant psychiatric disorder (all p > 0.05).
In conclusion, PRAs with or without concomitant psychiatric diagnoses are not associated with worse postoperative pain, functional outcomes, or satisfaction following MPFLR with allograft, dispelling common misconceptions that increased number of allergies or psychiatric diagnoses lead to inferior surgical outcomes. Presence of antibiotic allergies was associated with lower VAS postoperative pain score. Future research should investigate the relationship between PRAs and other surgeries in the field of sports medicine.
患者报告的过敏史(PRA)常被视为手术后疼痛加剧和功能预后较差的潜在不可改变的风险因素。然而,直接评估PRA对诸如内侧髌股韧带重建术(MPFLR)等运动手术预后影响的文献匮乏。我们研究的目的是确定PRA是否与MPFLR术后较差的预后相关。
我们对2011年至2019年在本机构接受MPFLR手术的患者进行了回顾性研究。如果患者至少有12个月的随访时间,则纳入研究。PRA从术前医学评估中获取,并按药物类别分类。人口统计学和围手术期数据从电子病历中获取。术后结果通过电话调查进行测量,包括复发性不稳定、疼痛视觉模拟量表(VAS)、运动VAS、库贾拉评分、MPFL损伤后恢复运动(MPFL-RSI)评分和总体满意度评分。采用多元线性回归确定PRA与结果指标之间的关联,p值小于0.05被认为具有统计学意义。
该队列包括141例MPFLR手术患者。大多数患者为女性(98例,70%),平均年龄25岁(范围12 - 56岁)。平均随访时间为47个月。47例患者(33%)报告至少有一种PRA。有或无PRA的患者在术后疼痛、功能结果、满意度或恢复运动方面无显著差异(所有p>0.05)。无抗生素PRA可预测较高的VAS评分(p<0.007),但无其他差异。无PRA的患者、无伴发精神疾病的PRA患者或伴有精神疾病的PRA患者在结果方面无显著差异(所有p>0.05)。
总之,伴有或不伴有精神疾病诊断的PRA与同种异体移植MPFLR术后较差的疼痛、功能结果或满意度无关,消除了关于过敏或精神疾病诊断数量增加会导致手术结果较差的常见误解。抗生素过敏与术后较低的VAS疼痛评分相关。未来的研究应调查PRA与运动医学领域其他手术之间的关系。