Department of Economics, University of Goettingen, Goettingen, 37073, Germany.
Centre for Modern Indian Studies, University of Goettingen, Goettingen, Germany.
Br J Nutr. 2023 Feb 14;129(3):416-427. doi: 10.1017/S0007114522000927. Epub 2022 Apr 6.
Despite several efforts by the Government of India, the national burden of anaemia remains high and its growing prevalence (between 2015-2016 and 2019-2021) is concerning to India's public health system. This article reviews existing food-based and clinical strategies to mitigate the anaemia burden and why they are premature and insufficient. In a context where multiple anaemia control programmes are in play, this article proposes a threefold strategy for consideration. First, except the Comprehensive National Nutrition Survey, 2016-2018, which measured Hb concentration among children and adolescents aged 1-19 years using venous blood samples, all national surveys use capillary blood samples to determine Hb levels, which could be erroneous. The Indian government should prioritise conducting a nationwide survey for estimating the burden of anaemia and its clinical determinants for all age groups using venous blood samples. Second, without deciding the appropriate dose of Fe needed for an individual, food fortification programmes that are often compounded with layering of other micronutrients could be harmful and further research on this issue is needed. Same is true for the pharmacological intervention of Fe tablet or syrup supplementation programmes, which is given to individuals without assessing its need. In addition, there is a dire need for robust research to understand both the long-term benefit and side effects of Fe supplementation programmes. Third and final, the WHO is in process of reviewing the Hb threshold for defining anaemia, therefore the introduction of new anaemia control programmes should be restrained.
尽管印度政府做出了多项努力,但其全国性贫血负担仍然很高,而且贫血的发病率(在 2015-2016 年至 2019-2021 年期间)令人担忧,这对印度公共卫生系统构成了挑战。本文回顾了现有的基于食物和临床的策略,以减轻贫血负担,以及为什么这些策略还不成熟且不足够。在存在多种贫血控制项目的背景下,本文提出了三重策略以供考虑。首先,除了 2016-2018 年综合国家营养调查使用静脉血样测量 1-19 岁儿童和青少年的 Hb 浓度外,所有国家调查都使用毛细血管血样来确定 Hb 水平,这可能是错误的。印度政府应该优先考虑进行一项全国性调查,使用静脉血样来估计所有年龄段的贫血负担及其临床决定因素。其次,在没有确定个体所需铁的适当剂量的情况下,食品强化计划通常会与其他微量营养素的叠加,这可能是有害的,因此需要对此问题进行进一步的研究。同样,对于铁片剂或糖浆补充计划的药物干预也是如此,在没有评估其需求的情况下,就将其给予个人。此外,迫切需要进行强有力的研究,以了解铁补充计划的长期效益和副作用。第三,也是最后一点,世卫组织正在审查定义贫血的 Hb 阈值,因此应限制引入新的贫血控制项目。