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患有显性甲状腺功能减退、亚临床甲状腺功能减退和甲状腺自身抗体阳性的孕妇的产前护理。

Antepartum Care for Pregnant People with Overt Hypothyroidism, Subclinical Hypothyroidism, and Positive Thyroid Autoantibodies.

作者信息

Mayhew Caitlin E, Simonson Kristin R, Ellsworth Bowers Esther R

机构信息

Nurse-Midwifery/Women's Health Nurse Practitioner and Women's Health Nurse Practitioner Programs, Georgetown University School of Nursing and Health Studies, Washington, DC.

出版信息

J Midwifery Womens Health. 2022 May;67(3):295-304. doi: 10.1111/jmwh.13306. Epub 2022 Apr 5.

Abstract

Maternal thyroid hormones are critical for the growth and development of a healthy fetus. During pregnancy, maternal thyroid hormone production is increased to meet the demands of fetal growth. The purpose of this review is to provide clinicians with current evidence about possible adverse maternal and fetal effects of hypothyroidism in pregnancy, including the role of hypothyroidism in recurrent pregnancy loss. In addition, clinical presentation, evidence-based screening guidelines, and evidence-based treatments are discussed.

摘要

母体甲状腺激素对健康胎儿的生长发育至关重要。在怀孕期间,母体甲状腺激素的分泌会增加以满足胎儿生长的需求。本综述的目的是为临床医生提供有关孕期甲状腺功能减退可能对母体和胎儿产生的不良影响的当前证据,包括甲状腺功能减退在复发性流产中的作用。此外,还讨论了临床表现、基于证据的筛查指南和基于证据的治疗方法。

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