Honnicke Miriam Beate, Tharun Lars, Sieren Malte Maria, Barkhausen Jörg
Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Institute of Pathology, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Discov Oncol. 2022 Apr 6;13(1):22. doi: 10.1007/s12672-022-00484-3.
Osteosarcomas are the most common primary malignant bone tumors and are classified by the WHO into several intramedullary and surface subtypes. One of these is the rare parosteal osteosarcoma. Liposarcomas are the second most common soft tissue sarcoma and are classified into several types ranging from intermediate to high grade tumors. In one of our recent patients we found an unusual combination of a parosteal osteosarcoma and a large fatty component, which fluorescence-in-situ-hybridization revealed as liposarcoma. Radiologists, pathologists, and surgeons should consider the possibility of bone and soft tissue malignancies consisting of different components, as this may be of paramount importance for oncologically complete resection.
骨肉瘤是最常见的原发性恶性骨肿瘤，世界卫生组织将其分为几种髓内和表面亚型。其中一种是罕见的骨旁骨肉瘤。脂肪肉瘤是第二常见的软组织肉瘤，分为几种类型，从中间级到高级别肿瘤。在我们最近的一名患者中，我们发现了骨旁骨肉瘤与大量脂肪成分的不寻常组合，荧光原位杂交显示为脂肪肉瘤。放射科医生、病理科医生和外科医生应考虑由不同成分组成的骨和软组织恶性肿瘤的可能性，因为这对于肿瘤学上的完整切除可能至关重要。
