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[单核吞噬细胞、止血系统与血管内凝血综合征]

[Mononuclear phagocytes, the hemostasis system and the intravascular coagulation syndrome].

作者信息

Tamarin I V

出版信息

Ter Arkh. 1986;58(9):130-7.

PMID:3538469
Abstract

The author analyses the reported data and his own findings concerned with the involvement of mononuclear phagocytes in the regulation of hemostasis and in the pathogenesis of a number of frequently occurring forms of the hemostatic system pathology. The content of monocytic thromboplastin was measured in 56 patients with the intravascular blood coagulation syndrome of varying etiology. Production of monocytic thromboplastin reached the highest degree in patients with purulent conditions whereas in patients presenting with the terminal stage of sepsis, it did not exceed normal or even dropped down, which may be connected with depletion of monocytes because of their preliminary hyperactivation.

摘要

作者分析了已报道的数据以及他自己的研究结果,这些数据和结果涉及单核吞噬细胞在止血调节以及多种常见止血系统病理形式的发病机制中的作用。对56例病因各异的血管内凝血综合征患者测定了单核细胞凝血活酶的含量。在化脓性疾病患者中,单核细胞凝血活酶的产生达到最高程度,而在脓毒症终末期患者中,其含量未超过正常水平,甚至有所下降,这可能与单核细胞因先前过度激活而耗竭有关。

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