Castro Nataly Echevarria, García Danitza Rojo, Rivera Midori Torpoco, Rondán-Guerrero Paola, García-Rojas Frank, Taype-Rondan Alvaro
Hospital Nacional Dos de Mayo, Lima, Perú.
Sociedad Científica de San Fernando, Universidad Nacional Mayor de San Marcos, Lima, Perú.
Rev Peru Med Exp Salud Publica. 2021 Oct-Dec;38(4):608-614. doi: 10.17843/rpmesp.2021.384.8820. Epub 2022 Apr 1.
This study aimed to evaluate the pharmacological trends in patients with COVID-19 from a hospital in Peru during the first wave of the pandemic. Retrospective study conducted between April and September 2020. The medical records of patients hospitalized for COVID-19 pneumonia at the Dos de Mayo National Hospital (Lima, Peru) were reviewed. Of a total of 3103 patients, 381 medical records were included (77.4% male, median age: 44 years). The use of four prehospital drugs increased (azithromycin, ivermectin, corticosteroids, and ceftriaxone), while the in-hospital use of six drugs (ceftriaxone, azithromycin, hydroxychloroquine, ivermectin, corticosteroid pulse, and prophylactic anticoagulation) decreased and in-hospital anticoagulation use decreased. These findings suggest that the management of COVID-19 has varied during the first wave of the pandemic, typically increasing prehospital drug use and decreasing inpatient use.
本研究旨在评估在大流行第一波期间，秘鲁一家医院中新冠肺炎患者的用药趋势。于2020年4月至9月进行回顾性研究。对秘鲁利马多斯德梅约国家医院因新冠肺炎肺炎住院患者的病历进行了审查。在总共3103名患者中，纳入了381份病历（男性占77.4%，中位年龄：44岁）。四种院前药物的使用增加（阿奇霉素、伊维菌素、皮质类固醇和头孢曲松），而六种院内药物（头孢曲松、阿奇霉素、羟氯喹、伊维菌素、皮质类固醇冲击治疗和预防性抗凝）的使用减少，且院内抗凝药物的使用也减少。这些发现表明，在大流行第一波期间，新冠肺炎的治疗方式有所不同，通常是院前药物使用增加，住院患者使用减少。
