Sightsavers, New Delhi 110020, India.
Sightsavers, 35 Perrymount Road, Haywards Heath RH16 3BZ, UK.
Int Health. 2022 Apr 6;14(Suppl 1):i29-i36. doi: 10.1093/inthealth/ihab078.
The number of patients with visual impairment and blindness from glaucoma is rapidly increasing with wide-ranging impacts for individuals and societies. However, the disease often goes undiagnosed for a long time, especially in low- and middle-income countries where healthcare services are limited. This paper presents the results of a pilot programme, which integrated targeted glaucoma screenings of people aged ≥40 y in community-based eye care services in the Ganjam district of Odisha state, India.
Using routine programme data, descriptive statistics were produced for the characteristics of patients participating in the screening programme and the rate and uptake of glaucoma referrals. Bivariate analysis was used to examine associations between patient characteristics, clinical risk factors and glaucoma diagnosis.
Out of 23 356 individuals aged ≥40 y screened for glaucoma over a period of 18 mo, 2219 (9.5%) were referred and 2031 presented for further examination. Among them, almost half (n=968, 48%) were diagnosed with glaucoma, representing a screening to diagnosis conversion rate of 4.14% (95% CI 3.9 to 4.4%). A positive diagnosis of glaucoma among suspects was associated with female sex, age >60 y, visual impairment, vertical cap-to-disc ratio ≥0.6:1, intraocular pressure ≥30 mmHg and shallow anterior chamber (p<0.001).
The importance of targeted screening for glaucoma using simple referral criteria to identify patients at high risk of vision loss who can benefit from treatment is critical to slow the progression of the disease and the prevention of blindness. Further studies assessing costs of the targeted screening, the role of technology in improving programme effectiveness and efficiency and the longer term compliance with treatment are needed to support glaucoma policy frameworks, guidelines and clinical practice.
由于青光眼导致的视力损害和失明患者数量正在迅速增加,对个人和社会都产生了广泛的影响。然而,这种疾病往往长期得不到诊断,尤其是在医疗服务有限的低收入和中等收入国家。本文介绍了一个试点项目的结果,该项目将针对印度奥里萨邦甘贾姆区社区眼保健服务中≥40 岁人群的目标性青光眼筛查纳入其中。
利用常规项目数据,对参与筛查项目的患者特征以及青光眼转诊的比例和接受情况进行了描述性统计。采用双变量分析来检查患者特征、临床危险因素与青光眼诊断之间的关联。
在 18 个月的时间里,对 23356 名≥40 岁的青光眼筛查对象进行了检查,其中 2219 人(9.5%)被转诊,2031 人前来进一步检查。其中,近一半(n=968,48%)被诊断为青光眼,筛查到诊断的转化率为 4.14%(95%CI 3.9 至 4.4%)。在疑似青光眼患者中,阳性诊断与女性、年龄>60 岁、视力损害、垂直杯盘比≥0.6:1、眼压≥30mmHg 和浅前房(p<0.001)有关。
使用简单的转诊标准对青光眼进行有针对性的筛查,以确定有视力丧失风险并可从中受益于治疗的高危患者,对于减缓疾病进展和预防失明至关重要。还需要进一步研究评估有针对性筛查的成本、技术在提高项目效果和效率方面的作用以及长期治疗的依从性,以为青光眼政策框架、指南和临床实践提供支持。