[基于人群筛查数据的抗链球菌脂蛋白酶型特异性抗体分布]

[Distribution of type-specific antibodies to streptococcal lipoproteinase based on population screening data].

作者信息

Benevolenskaia L I, Iontova I M, Burlev A A, Totolian A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1986 Sep(9):61-6.

Abstract

In the serum samples obtained from residents of the Todzhinsky district in the Tuva Autonomous Soviet Socialist Republic antibodies to 12 out of 15 studied types of group A streptococcal lipoproteinases (OF-factor) were detected, with the prevalence of types 2, 4, 22, 25, 48, and 60, their incidence in the population constituting 34%. Antibodies to OF-antigens 58, 62, and 63 were not detected. The distribution of OF-antibodies was found to vary with sex, occurring in females 1.5 times more frequently than in males, and with age, accumulating in subjects aged 21-30 and 31-40. The distribution of antibodies to different OF serotypes did not depend on the blood serum streptolysin O titers.

摘要

在从图瓦自治苏维埃社会主义共和国托金斯基区居民采集的血清样本中，检测到了15种研究的A组链球菌脂蛋白酶（OF因子）类型中的12种抗体，其中2型、4型、22型、25型、48型和60型最为常见，它们在人群中的发病率为34%。未检测到针对OF抗原58、62和63的抗体。发现OF抗体的分布因性别而异，女性出现的频率是男性的1.5倍，并且因年龄而异，在21 - 30岁和31 - 40岁的人群中积累。针对不同OF血清型的抗体分布不依赖于血清抗链球菌溶血素O滴度。