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病例报告：一名肺腺癌患者的类Purtscher视网膜病变

Case Report: Purtscher-like retinopathy in a patient with lung adenocarcinoma.

作者信息

Mahmoud Anis, Zaghdoudi Asma, Boucharb Soumaya, Abid Fatma, Mbarek Sameh, Ibn Hadj Amor Hassan, Braiek Sawssen, Keskes Boudawara Nadia, Knani Jalel, Messaoud Riadh

机构信息

ophtalmology, Taher Sfar University Hospital, Mahdia, Mahdia, 5100, Tunisia.

Faculty of Medicine, University of Monastir, Monastir, Tunisia.

出版信息

F1000Res. 2022 Feb 24;11:227. doi: 10.12688/f1000research.74917.1. eCollection 2022.

DOI:10.12688/f1000research.74917.1
PMID:35388336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8941289/
Abstract

This case report describes an unreported case of  Purtscher-like retinopathy in a patient with pulmonary adenocarcinoma. A 39-year-old man was hospitalized for exploration of a hemoptysis and bilateral blurry vision. Fundoscopic examination showed multiple areas of retinal whitening in the peripapillary area. A chest computed tomography scan then showed a ground glass opacity in the right upper lobe associated to a hilar lymphadenopathy. A thoracotomy and lung biopsy were performed concluding with the diagnosis of lung adenocarcinoma. The patient was treated with high-dose corticosteroids and received Taxol-Carboplatin chemotherapy with good visual outcomes. The article discusses furthermore the importance of including pulmonary adenocarcinoma to the list of systemic conditions for Purtscher-like retinopathy.

摘要

本病例报告描述了一例未报道过的肺腺癌患者发生的类Purtscher视网膜病变。一名39岁男性因咯血和双眼视物模糊入院检查。眼底检查显示视乳头周围区域有多个视网膜变白区。随后胸部计算机断层扫描显示右上叶磨玻璃影伴肺门淋巴结肿大。进行了开胸手术及肺活检，最终诊断为肺腺癌。该患者接受了大剂量皮质类固醇治疗，并接受了紫杉醇-卡铂化疗，视力恢复良好。本文还讨论了将肺腺癌纳入类Purtscher视网膜病变全身性疾病列表的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/fb911d1487fc/f1000research-11-78721-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/281a1754b50e/f1000research-11-78721-g0000.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/d248b33c06d7/f1000research-11-78721-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/9ac9b89f0f72/f1000research-11-78721-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/f6737126f4bb/f1000research-11-78721-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/fb911d1487fc/f1000research-11-78721-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/281a1754b50e/f1000research-11-78721-g0000.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/d248b33c06d7/f1000research-11-78721-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/9ac9b89f0f72/f1000research-11-78721-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/f6737126f4bb/f1000research-11-78721-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/165d/8941289/fb911d1487fc/f1000research-11-78721-g0004.jpg

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本文引用的文献

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Oncologist. 2018 Nov;23(11):1372-1381. doi: 10.1634/theoncologist.2017-0530. Epub 2018 Aug 13.
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Purtscher-like retinopathy associated with squamous cell carcinoma of the cervix.与宫颈癌相关的类Purtscher样视网膜病变。
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Central retinal artery occlusion, an early sign of crizotinib resistance in an alk positive adenocarcinoma of lung: A rare case report.
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Purtscher-like retinopathy in association with metastatic pancreatic adenocarcinoma and capecitabine therapy.与转移性胰腺腺癌及卡培他滨治疗相关的类Purtscher样视网膜病变
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