Department of Otolaryngology, Warwick Hospital, Warwick, UK.
J Laryngol Otol. 2022 Dec;136(12):1259-1264. doi: 10.1017/S0022215122000470. Epub 2022 Apr 7.
Unilateral maxillary sinus opacification on computed tomography may reflect an inflammatory or neoplastic process. The neoplasia risk is not clear in the literature.
In this retrospective study, computed tomography sinus scans performed over 12 months were screened for unilateral maxillary sinus opacification, and the rates of inflammatory and neoplastic diagnoses were calculated.
Of 641 computed tomography sinus scans, the rate of unilateral maxillary sinus opacification was 9 per cent. Fifty-two cases were analysed. The risk of neoplasia was 2 per cent (inverted papilloma, = 1). No cases of unilateral maxillary sinus opacification represented malignancy, but one case of lymphoma had an incidental finding of unilateral maxillary sinus opacification on the contralateral side. Patients with an antrochoanal polyp ( = 3), fungal disease ( = 1), inverted papilloma and lymphoma all had a unilateral nasal mass.
Our neoplasia rate of 2 per cent was lower than previously reported. A unilateral mass was predictive of pathology that required operative management. Clinical findings, rather than simple findings of opacification on computed tomography, should drive the decision to perform biopsy.
计算机断层扫描（CT）显示单侧上颌窦混浊可能反映了炎症或肿瘤过程。文献中尚不清楚肿瘤的发病风险。
在这项回顾性研究中，对 12 个月内进行的 CT 鼻窦扫描进行筛选，以发现单侧上颌窦混浊，并计算炎症和肿瘤的诊断率。
在 641 例 CT 鼻窦扫描中，单侧上颌窦混浊的发生率为 9%。对 52 例病例进行了分析。肿瘤的发病风险为 2%（内翻性乳头状瘤， = 1）。单侧上颌窦混浊无一例为恶性肿瘤，但一例淋巴瘤在对侧出现单侧上颌窦混浊的偶发发现。患有上颌窦后鼻孔息肉（ = 3）、真菌病（ = 1）、内翻性乳头状瘤和淋巴瘤的患者均有单侧鼻腔肿块。
我们的肿瘤发病率为 2%，低于以往报道。单侧肿块预示着需要手术治疗的病变。应该根据临床发现，而不是 CT 上单纯的混浊发现来决定是否进行活检。
