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基于STOP-BANG问卷的冠状动脉受累严重程度和复杂性与阻塞性睡眠呼吸暂停之间的关系

Relationship between Severity and Complexity of Coronary Artery Involvement and Obstructive Sleep Apnea Based on STOP-BANG Questionnaire.

作者信息

Naghshtabrizi Nima, Alizadeh Soroosh, Naghshtabrizi Behshad, Jalali Arash, Salarifar Mojtaba

机构信息

Department of Cardiology, Tehran University of Medical Science, Tehran, Iran.

Department of Cardiology, Hamadan University of Medical Science, Hamadan, Iran.

出版信息

Int J Prev Med. 2022 Feb 23;13:34. doi: 10.4103/ijpvm.IJPVM_443_19. eCollection 2022.

Abstract

BACKGROUND

Obstructive sleep apnea (OSA), which has a known correlation with cardiovascular disease, is a possible risk factor of coronary artery disease (CAD) that is preventable.

AIMS

We sought to put lights on the relationship between OSA based on the STOP-BANG questionnaire (SBQ) and the severity and complexity of coronary artery involvement.

METHODS

This cross-sectional, single-center, retrospective study was conducted among 145 patients who underwent selective coronary angiography (SCA) between October 2018 and March 2019, admitted to the Tehran Heart Center, Tehran, Iran. OSA risk was assessed in patients based on SBQ categories. Also, the severity and complexity of coronary artery involvement calculated according to SYNTAX and Gensini scores. Analysis performed by statistical software SPSS 25.

RESULTS

Based on SBQ risk assessment categories, 22 (15.2%), 64 (44.1%), and 59 (40.7%) of the patients were low, intermediate, and high-risk for OSA, respectively. By comparing the means of coronary artery involvement, there was no significant difference in SYNTAX score 17.15 ± 13.67 (10.56-23.74) in low, 15.67 ± 9.78 (13.19-18.16) in intermediate, and 16.93 ± 9.21 (14.42-19.45) in high-risk groups; P value: 0.754, and Gensini score 66.4 ± 70.75 (35.04-97.77) in low, 66.21 ± 55.05 (52.45-79.96) in intermediate, 74.61 ± 56.33 (59.93-89.3) iin high risk groups; P value: 0.697 with groups of OSA risks. Also, after adjusting confounding factors, there was still no statistically significant difference in terms of coronary involvement scores.

CONCLUSIONS

There was no statistically significant difference in SYNTAX and Gensini scores of different groups of OSA risk categories based on the SBQ. However, our results can't be extended into the connection between OSA and CAD.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)与心血管疾病存在已知关联,是冠状动脉疾病(CAD)的一个可预防的潜在危险因素。

目的

我们试图基于STOP - BANG问卷(SBQ)揭示OSA与冠状动脉受累的严重程度和复杂性之间的关系。

方法

本横断面、单中心、回顾性研究在2018年10月至2019年3月期间于伊朗德黑兰心脏中心接受选择性冠状动脉造影(SCA)的145例患者中进行。根据SBQ类别评估患者的OSA风险。此外,根据SYNTAX和Gensini评分计算冠状动脉受累的严重程度和复杂性。使用统计软件SPSS 25进行分析。

结果

根据SBQ风险评估类别,患者中分别有22例(15.2%)、64例(44.1%)和59例(40.7%)为OSA低、中、高风险。通过比较冠状动脉受累的均值,低风险组的SYNTAX评分为17.15±13.67(10.56 - 23.74),中风险组为15.67±9.78(13.19 - 18.16),高风险组为16.93±9.21(14.42 - 19.45);P值:0.754;低风险组的Gensini评分为66.4±70.75(35.04 - 97.77),中风险组为66.21±55.05(52.45 - 79.96),高风险组为74.61±56.33(59.93 - 89.3);P值:0.697,不同OSA风险组之间比较。此外,在调整混杂因素后,冠状动脉受累评分方面仍无统计学显著差异。

结论

基于SBQ的不同OSA风险类别组的SYNTAX和Gensini评分无统计学显著差异。然而,我们的结果不能推广到OSA与CAD之间的联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b6/8980830/6bc1ac8dfb5e/IJPVM-13-34-g001.jpg

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