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诊断、处理和人工尿道括约肌装置相关囊袋导致的尿道梗阻的转归。

Diagnosis, management, and outcome of urethral obstruction secondary to the capsule associated with the artificial urethral sphincter device.

机构信息

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

出版信息

J Vet Intern Med. 2022 May;36(3):1016-1023. doi: 10.1111/jvim.16399. Epub 2022 Apr 8.

DOI:10.1111/jvim.16399
PMID:35393653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9151471/
Abstract

BACKGROUND

Urethral obstruction secondary to artificial urethral sphincter (AUS) implantation is a recognized complication in dogs. However, urethral obstruction secondary to AUS-associated capsule formation has been described rarely.

HYPOTHESIS

Describe clinical and diagnostic findings, management, and outcome in 6 dogs with urethral obstruction secondary to AUS-associated capsule formation.

ANIMALS

Six client-owned dogs.

METHODS

Retrospective study. Medical records between January 1, 2010, and June 30, 2021, were reviewed to identify dogs with urethral obstruction associated with the AUS device.

RESULTS

The AUS device was implanted a median of 884 days (range, 20-2457 days) before presentation for urethral obstruction. Median age at time of urethral obstruction was 4.7 years (range, 3.1-8.7 years). Clinical signs at the time of urethral obstruction were stranguria (n = 4), pollakiuria (3), weak urine stream (2), and worsened urinary incontinence (1). In all dogs, the urethra was noted to be stenotic during urethroscopy and positive contrast cystourethrography. All dogs underwent surgery, and a fibrous capsule associated with the AUS was found to be causing urethral stenosis. Resolution of urethral obstruction occurred in all dogs after transection or removal of the capsule. Positive bacterial cultures were obtained from the capsule, AUS, or both in all dogs. Recurrence of urethral obstruction had not occurred in any dog at the time of follow-up.

CONCLUSIONS AND CLINICAL IMPORTANCE

Urethral obstruction secondary to capsule formation is an uncommon but clinically important complication associated with use of the AUS. Continued investigation is needed to evaluate this complication more thoroughly, and its possible association with infection.

摘要

背景

人工尿道括约肌(AUS)植入后发生尿道梗阻是犬的一种公认并发症。然而,与 AUS 相关的囊形成引起的尿道梗阻很少被描述。

假设

描述 6 只因 AUS 相关囊形成导致尿道梗阻的犬的临床和诊断发现、治疗和结局。

动物

6 只患犬。

方法

回顾性研究。回顾 2010 年 1 月 1 日至 2021 年 6 月 30 日期间的病历,以确定与 AUS 装置相关的尿道梗阻犬。

结果

AUS 装置植入后出现尿道梗阻的中位时间为 884 天(范围,20-2457 天)。出现尿道梗阻时的中位年龄为 4.7 岁(范围,3.1-8.7 岁)。尿道梗阻时的临床症状为排尿困难(4 只)、多尿(3 只)、尿流弱(2 只)和尿失禁加重(1 只)。在所有犬中,尿道镜检查和阳性对比膀胱尿道造影均发现尿道狭窄。所有犬均接受了手术,发现与 AUS 相关的纤维囊导致尿道狭窄。在所有犬中,囊切开或切除后尿道梗阻均得到缓解。所有犬的囊、AUS 或两者均获得了阳性细菌培养。在随访时,没有犬再次发生尿道梗阻。

结论和临床意义

囊形成引起的尿道梗阻是使用 AUS 后一种罕见但具有重要临床意义的并发症。需要进一步研究以更全面地评估这种并发症及其与感染的可能关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/eb3e8992252b/JVIM-36-1016-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/176861b8520f/JVIM-36-1016-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/648686c57b1d/JVIM-36-1016-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/eb3e8992252b/JVIM-36-1016-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/176861b8520f/JVIM-36-1016-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/648686c57b1d/JVIM-36-1016-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c23/9151471/eb3e8992252b/JVIM-36-1016-g002.jpg

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