Alıcı Gökhan, Waberi Mohamud Mire, Mohamud Mohamed Abdullahi, Bashir Ahmed Muhammad, Genç Ömer
Department of Cardiology, Turkey Recep Tayyip Erdogan, Somalia Mogadishu Training and Research Hospital, Mogadishu, Somalia.
Department of Cardiology, Agri Training and Research Hospital, Agri, Turkey.
Egypt Heart J. 2022 Apr 8;74(1):24. doi: 10.1186/s43044-022-00261-1.
This study aims to examine the prevalence and related factors of pulmonary hypertension (PHT) in patients on hemodialysis (HD) at the only referral institution in Somalia. A total of one hundred and forty-three patients who had received regular HD therapy for at least three months and underwent transthoracic echocardiography (TTE) were included in the study. Patients with a systolic pulmonary artery pressure (sPAP) value > 35 mmHg at rest on TTE were considered having PHT. The relationship of TTE parameters, demographic, and clinic characteristics of participants with PHT were evaluated.
The number of patients with PHT was 73 (51%). The mean age was 54.2 ± 18.4 years. The majority of patients were 65 years of age or older. (n: 46, 32.2%) and 65 (45.5%) were male. Median sPAP was found to be 35 mmHg. Systolic pulmonary artery pressure was positively correlated with right atrium (RA) diameter (r: 0.6, p < 0.001) and negatively correlated with left ventricular ejection fraction (LVEF) (r: - 0.4, p < 0.001). In addition, LVEF, RA diameter, presence of pericardial effusion (PE) were found to be independent predictors of PHT.
Pulmonary hypertension has a relatively high prevalence in end-stage renal disease (ESRD) patients on regular HD. Besides, the presence of PE and certain right and left heart parameters were independently associated with PHT.
本研究旨在调查索马里唯一一家转诊机构中接受血液透析（HD）患者的肺动脉高压（PHT）患病率及相关因素。共有143例接受规律血液透析治疗至少3个月并接受经胸超声心动图（TTE）检查的患者纳入本研究。经胸超声心动图检查静息时收缩期肺动脉压（sPAP）值>35 mmHg的患者被视为患有肺动脉高压。评估了经胸超声心动图参数、参与者的人口统计学和临床特征与肺动脉高压的关系。
肺动脉高压患者有73例（51%）。平均年龄为54.2±18.4岁。大多数患者年龄在65岁及以上（n = 46，32.2%），男性65例（45.5%）。收缩期肺动脉压中位数为35 mmHg。收缩期肺动脉压与右心房（RA）直径呈正相关（r = 0.6，p < 0.001），与左心室射血分数（LVEF）呈负相关（r = -0.4，p < 0.001）。此外，左心室射血分数、右心房直径、心包积液（PE）的存在被发现是肺动脉高压的独立预测因素。
规律血液透析的终末期肾病（ESRD）患者中肺动脉高压患病率相对较高。此外，心包积液的存在以及某些左右心参数与肺动脉高压独立相关。
