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[关于癫痫患者自主神经功能障碍的当前概念]

[Current concepts about autonomic dysfunction in patients with epilepsy].

作者信息

Zhuravlev D V, Lebedeva A V, Lebedeva M A, Guekht A B

机构信息

Moscow Research and Clinical Center for Neuropsychiatry, Moscow, Russia.

Pirogov Russian National Research Medical University, Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(3):131-138. doi: 10.17116/jnevro2022122031131.

Abstract

Autonomic dysfunction is frequently observed in people with epilepsy. Ictal and postictal dysautonomia is not only manifestation of autonomic seizures, but could be a life threatening condition in some cases and contribute to sudden unexpected death (SUDEP). Interictal decrease of autonomic activity is associated with duration and severity of epilepsy, it is the most prominent in focal and drug-resistant epilepsy. Progress in our understanding of the underlying mechanisms, development of the autonomic assessment methods, and its integration in novel technical solutions for seizure detection will improve the quality of care for people with epilepsy.

摘要

自主神经功能障碍在癫痫患者中很常见。发作期和发作后期自主神经功能异常不仅是自主神经发作的表现,在某些情况下可能是危及生命的状况,并导致癫痫猝死(SUDEP)。发作间期自主神经活动的降低与癫痫的病程和严重程度相关,在局灶性和耐药性癫痫中最为显著。我们对潜在机制认识的进展、自主神经评估方法的发展及其在癫痫发作检测新技术方案中的整合,将提高癫痫患者的护理质量。

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