Plants for Human Health Institute, Food Bioprocessing and Nutrition Sciences Department, North Carolina State University, North Carolina Research Campus, Kannapolis, North Carolina 28081, United States.
Arkansas Childrens Nutrition Center and University of Arkansas for Medical Sciences, Little Rock, Arkansas 72202, United States.
J Agric Food Chem. 2022 Oct 19;70(41):13017-13026. doi: 10.1021/acs.jafc.2c00398. Epub 2022 Apr 8.
Protein-polyphenol aggregate particles concurrently fortify a functional food product with healthy dietary proteins and concentrated polyphenols. However, what impact does ingestion of aggregate particles have on ultimate health relevance of either the polyphenolic molecules in the matrix or the protein molecules? Because human health benefits are contingent on bioavailability after ingestion, the fate of these molecules during transit in the gastrointestinal tract (GIT) will dictate their utility as functional food ingredients. This brief review explores diverse applications of protein-polyphenol particles in the food industry and the bioaccessibility of both bioactive polyphenolic compounds and edible proteins. Evidence to date suggests that complexation of phytoactive polyphenolics effectively enhances their health-relevant impacts, specifically because the phytoactives are protected in the protein matrix during transit in the GIT, allowing intact, non-degraded molecules to reach the colon for catabolism at the gut microbiome level, a prerequisite to realize the health benefits of these active compounds.
蛋白-多酚聚集颗粒同时为功能性食品产品提供健康的膳食蛋白质和浓缩多酚。然而，摄入聚集颗粒会对基质中的多酚分子或蛋白质分子的最终健康相关性产生什么影响？因为人类健康益处取决于摄入后的生物利用度，这些分子在胃肠道 (GIT) 中的转运过程中的命运将决定它们作为功能性食品成分的用途。本综述探讨了蛋白-多酚颗粒在食品工业中的多种应用，以及生物活性多酚化合物和可食用蛋白质的生物可及性。目前的证据表明，植物活性多酚的复合有效地增强了它们的健康相关影响，特别是因为在 GIT 转运过程中，植物活性物质被蛋白质基质所保护，使完整的、未降解的分子能够到达结肠，在肠道微生物组水平上进行代谢，这是实现这些活性化合物健康益处的前提。
