Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Subst Abuse Treat Prev Policy. 2022 Apr 9;17(1):27. doi: 10.1186/s13011-022-00453-7.
Methamphetamine use in men who have sex with men population is significantly higher than that in the general population. Meth use can cause high-risk sexual behaviors, such as having sex with a variety of sexual partners. The aim of this study was to determine the association between meth use and the number of sexual partners in MSM.
Searching international databases (PubMed (Medline), Scopus, Web of Sciences, Embase (Elsevier), PsycInfo (Ovid), Cochrane CENTRAL (Ovid)) until March 2021 was performed in this meta-analysis using appropriate keywords terms to identify related articles. After retrieving articles in these databases, screening was performed based on the title, abstract and full text of the articles, and the final related studies were selected and evaluated using the Newcastle Ottawa scale checklist.
The sample size consisted 18,455 people in this study, including four cohort studies with a sample size of 15,026 MSM and four case-control studies with a sample size of 3429 MSM. The results of meta-analysis showed that meth use increased the number of sexual partners in MSM (RR: 3.70; % 95 CI: 2.04-6.70). The results of subgroup analyze based on the number of sexual partners showed that in MSM taking meth, the risks of having one to three, four to five, and six or more than six sexual partners were respectively 2.82, 2.98 and 5.89 times higher than those in MSM who did not take meth.
The results showed that meth uses in MSM increased the number of their sexual partners. Due to the fact that increasing the number of sexual partners and high-risk sexual behaviors increase the risk of contracting sexually transmitted diseases such as HIV, it is necessary to adopt control programs to prevent meth use by this group, or to implement programs of reduction in the risk of STIs for this group.
男男性行为人群（MSM）中使用冰毒的比例显著高于一般人群。冰毒的使用可能导致高危性行为，例如与各种性伴侣发生性行为。本研究旨在确定 MSM 中冰毒使用与性伴侣数量之间的关联。
本荟萃分析通过使用适当的关键词搜索国际数据库（PubMed（Medline）、Scopus、Web of Sciences、Embase（Elsevier）、PsycInfo（Ovid）、Cochrane CENTRAL（Ovid）），直到 2021 年 3 月，以确定相关文章。在这些数据库中检索文章后，根据文章的标题、摘要和全文进行筛选，并使用纽卡斯尔-渥太华量表检查表选择和评估最终相关研究。
本研究的样本量包括 18455 人，其中包括四项队列研究，样本量为 15026 名 MSM，以及四项病例对照研究，样本量为 3429 名 MSM。荟萃分析结果表明，冰毒使用增加了 MSM 的性伴侣数量（RR：3.70；95%CI：2.04-6.70）。基于性伴侣数量的亚组分析结果表明，在使用冰毒的 MSM 中，与未使用冰毒的 MSM 相比，与一个至三个、四个至五个和六个或更多性伴侣发生性行为的风险分别高 2.82、2.98 和 5.89 倍。
结果表明，冰毒的使用增加了 MSM 的性伴侣数量。由于增加性伴侣数量和高危性行为会增加感染 HIV 等性传播疾病的风险，因此有必要采取控制方案来预防该人群使用冰毒，或为该人群实施减少性传播感染风险的方案。
