Inflammation Centre, Division of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Inflammation Centre, Division of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
J Hosp Infect. 2022 Jul;125:55-59. doi: 10.1016/j.jhin.2022.03.012. Epub 2022 Apr 7.
Recently, new non-alcohol-based hand disinfection formulae have come to the market. Although they have passed the EN1500 test, data on their clinical efficacy compared with alcohol-based hand rubs are scarce, mainly covering benzalkonium chloride (BAC).
To test the efficacy of silver-polymer-based, lactic-acid-based and BAC-based hand disinfectant foams and an alcohol-based hand rub gel to reduce bacterial counts on the fingertips of healthcare workers working on hospital wards.
Each of the 84 participants tested one of the four products during their morning shift on a hospital ward using the 'fingertips on Petri dish' method before and after rubbing their hands with the product. After incubation, two independent readers assessed bacterial counts on the culture plates.
The alcohol-based hand rub efficiently reduced bacteria on testers' fingertips in the test situation, whereas the lactic-acid- and BAC-based disinfectants did not have any detectable efficacy. The silver-polymer-based formula had some effect but requires further study.
Non-alcohol-based hand rubs require careful consideration and further study before they can be accepted for clinical use.
最近，市场上出现了一些新型的非酒精基手部消毒剂。虽然这些产品已经通过了 EN1500 测试，但与酒精基手部搓手液相比，它们的临床效果数据相对较少，主要涵盖苯扎氯铵（BAC）。
测试基于银聚合物、乳酸基和 BAC 的手部消毒泡沫以及一种酒精基手部搓手凝胶在减少医院病房工作的医护人员指尖细菌数量方面的功效。
84 名参与者中的每一位在医院病房的早晨轮班期间使用“指尖在培养皿上”的方法，在使用产品前后擦拭双手，测试四种产品中的一种。孵育后，两名独立的读者评估培养皿上的细菌计数。
在测试环境下，酒精基手部搓手液能有效减少测试者指尖的细菌，而乳酸基和 BAC 基消毒剂则没有任何可检测到的效果。基于银聚合物的配方有一定效果，但需要进一步研究。
非酒精基手部消毒剂在被接受用于临床使用之前需要仔细考虑和进一步研究。
