Shukla Richa, Kar Sujita Kumar, Dalal P K, Arya Amit
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Indian J Psychiatry. 2022 Jan-Feb;64(1):56-63. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_682_21. Epub 2022 Jan 21.
Patients with opioid use disorder (OUD) have a significant problem in psychosocial functioning domains, which are not systematically studied in India. This study aimed to evaluate the psychosocial functioning in current noninjecting opioid users on Methadone Maintenance Treatment (MMT) versus Treatment as Usual (TaU: , , , , , ).
It is a cross-sectional study on patients of current noninjecting OUD on MMT or TaU for at least in the past month. Comorbidities and illness severity were assessed with the help of Mini-International Neuropsychiatric Interview 7.0.2 and World Health Organization-The Alcohol, Smoking, and Substance Involvement Screening Test 3.0, respectively. Social and occupational functioning assessment scale (SOFAS), WHO Quality of Life (WHOQoL-BREF), and Client Satisfaction Questionnaire (CSQ-8) assessed the sociooccupational functioning and QoL and client satisfaction. A total of 67 participants (37 on MMT and 30 on TaU) were included in the study.
A significant difference between the two groups (MMT better than TaU) was based on SOFAS scores, CSQ-8, and WHOQoL-BREF. In the TaU group, there was a significant negative correlation between risk of addiction severity with sociooccupational functioning ( = -0.5; = 0.0046), physical health ( = -0.48; = 0.0087) and social relationship ( = -0.47; = 0.0087) domain of QoL. In the MMT group, the association between risk of addiction severity with sociooccupational functioning, domains of QoL, and client satisfaction were insignificant.
Sociooccupational Functioning, Client Satisfaction, and QoL of patients maintained on MMT are better than those on TaU.
阿片类物质使用障碍（OUD）患者在心理社会功能领域存在重大问题，而印度尚未对这些领域进行系统研究。本研究旨在评估接受美沙酮维持治疗（MMT）的当前非注射用阿片类物质使用者与常规治疗（TaU： ， ， ， ， ， ）相比的心理社会功能。
这是一项针对过去至少一个月接受MMT或TaU治疗的当前非注射用OUD患者的横断面研究。分别借助迷你国际神经精神访谈7.0.2和世界卫生组织-酒精、吸烟和物质使用筛查测试3.0评估合并症和疾病严重程度。社会和职业功能评估量表（SOFAS）、世界卫生组织生活质量量表（WHOQoL-BREF）和客户满意度问卷（CSQ-8）评估社会职业功能、生活质量和客户满意度。本研究共纳入67名参与者（37名接受MMT治疗，30名接受TaU治疗）。
两组之间（MMT组优于TaU组）在SOFAS评分、CSQ-8和WHOQoL-BREF方面存在显著差异。在TaU组中，成瘾严重程度风险与社会职业功能（ = -0.5； = 0.0046）、身体健康（ = -0.48； = 0.0087）以及生活质量的社会关系领域（ = -0.47； = 0.0087）之间存在显著负相关。在MMT组中，成瘾严重程度风险与社会职业功能、生活质量领域以及客户满意度之间的关联不显著。
接受MMT维持治疗的患者的社会职业功能、客户满意度和生活质量优于接受TaU治疗的患者。
