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曲马多用于阿片类物质使用障碍管理:理论依据与建议

Use of Tramadol for Management of Opioid Use Disorders: Rationale and Recommendations.

作者信息

Balhara Yatan Pal Singh, Parmar Arpit, Sarkar Siddharth

机构信息

Department of Psychiatry and National Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Neurosci Rural Pract. 2018 Jul-Sep;9(3):397-403. doi: 10.4103/jnrp.jnrp_42_18.

DOI:10.4103/jnrp.jnrp_42_18
PMID:30069098
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6050785/
Abstract

Opioids are one of the most common illicit psychoactive substances being used in India. In fact, opioid use disorders are the most common disorder presenting to the substance use disorder treatment centers across the country. Effective and evidence-based interventions are available for management of opioid use disorders. However, the treatment for opioid use disorders remains difficult to access for most of those in need in India. The current article presents the literature on the use of tramadol for the management of opioid use disorders. It also makes recommendations on the use of tramadol for the management of opioid use disorders. Tramadol offers a viable alternative to the existing options for the management of opioid use disorders. It has been found effective when used for this indication. It offers certain major advantages such as easy and wide availability and low abuse liability. It offers a good option to expand the treatment services for opioid use disorders across the country.

摘要

阿片类药物是印度最常用的非法精神活性物质之一。事实上,阿片类药物使用障碍是全国物质使用障碍治疗中心最常见的疾病。有有效的循证干预措施可用于管理阿片类药物使用障碍。然而,在印度,大多数有需要的人仍难以获得阿片类药物使用障碍的治疗。本文介绍了关于曲马多用于管理阿片类药物使用障碍的文献。它还就曲马多用于管理阿片类药物使用障碍提出了建议。曲马多为现有的阿片类药物使用障碍管理方案提供了一个可行的替代选择。已发现其用于该适应症时有效。它具有一些主要优点,如易于广泛获取且滥用可能性低。它为在全国范围内扩大阿片类药物使用障碍的治疗服务提供了一个好的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/661b/6050785/c72a29e1e4eb/JNRP-9-397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/661b/6050785/c72a29e1e4eb/JNRP-9-397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/661b/6050785/c72a29e1e4eb/JNRP-9-397-g002.jpg

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J Opioid Manag. 2017 Sep/Oct;13(5):329-334. doi: 10.5055/jom.2017.0401.
2
Maintainence Treatment of Opioid Dependence with Tramadol.曲马多用于阿片类物质依赖的维持治疗
J Neurosci Rural Pract. 2017 Aug;8(Suppl 1):S98-S101. doi: 10.4103/jnrp.jnrp_422_16.
3
Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial.曲马多缓释片用于阿片类药物戒断的疗效:一项随机临床试验。
印度注射吸毒人群中的 HIV、乙型肝炎和丙型肝炎:区域异质性的系统评价及阿片类药物替代治疗概述。
Indian J Med Res. 2023 Nov 1;158(5&6):522-534. doi: 10.4103/ijmr.ijmr_1930_23. Epub 2024 Jan 24.
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Pharmacovigilance Signals of the Opioid Epidemic over 10 Years: Data Mining Methods in the Analysis of Pharmacovigilance Datasets Collecting Adverse Drug Reactions (ADRs) Reported to EudraVigilance (EV) and the FDA Adverse Event Reporting System (FAERS).十年阿片类药物流行的药物警戒信号:用于分析向欧洲药品不良反应数据库(EudraVigilance,EV)和美国食品药品监督管理局不良事件报告系统(FAERS)报告的药物不良反应(ADR)的药物警戒数据集的数据挖掘方法
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