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混合鼻填充物:琼脂糖凝胶与透明质酸联合用于非手术隆鼻术

Hybrid Nasal Filler: Combining Agarose Gel and Hyaluronic Acid for Nonsurgical Rhinoplasty.

作者信息

Buhsem Omer, Kirazoglu Ahmet

机构信息

Plastic, Reconstructive and Aesthetic Surgery, Private Practice, Bursa, Turkey.

Department of Plastic, Reconstructive and Aesthetic Surgery, Bezmialem Vakif University Medical Faculty, Istanbul, Turkey.

出版信息

Plast Reconstr Surg Glob Open. 2022 Apr 6;10(4):e4236. doi: 10.1097/GOX.0000000000004236. eCollection 2022 Apr.

DOI:10.1097/GOX.0000000000004236
PMID:35402124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8987220/
Abstract

UNLABELLED

Given its structural properties, it would be a mistake to assume that a single type of filler fits perfectly to each anatomical region of the nose in nonsurgical rhinoplasty procedures. Therefore, we aimed to develop a hybrid treatment model by applying two different structural types of fillers. Hyaluronic acid (HA), a hydrophilic material, and agarose gel (AG), a nonhydrophilic and high G-prime material, were used in the study according to their advantages and disadvantages.

METHODS

Patients who presented to the office desiring filler treatment for nonsurgical correction of the nose in a 2-year period were enrolled in the study. HA was used intradermally 0.1 ml per each point in the tip defining points and supratip. Injections of 0.4-0.7 and 0.4-0.6 ml AG were used supraperiosteally in the radix and nasal spine, respectively. Clinical improvement was evaluated two weeks later using the Global Aesthetic Improvement Scale from 1 to 5 (1: exceptional improvement; 5: worsened patient). Patient satisfaction was evaluated on a scale from 0 to 10 (0: not satisfied; 10: very satisfied).

RESULTS

A total of 32 patients (mean age: 27 years) were enrolled in the study. Mean score of patient satisfaction was 9.09 of 10 after injection and 9 of 10 after 2 weeks. Clinical evaluation scores after injection were 1.72 of 5 and 1.69 of 5 on the Global Aesthetic Improvement Scale. No major complication was observed.

CONCLUSION

The HA and AG filler hybrid concept applied in different anatomical locations represents a safe and convenient option for nonsurgical rhinoplasty procedures.

摘要

未标注

鉴于其结构特性,在非手术隆鼻手术中假设单一类型的填充剂能完美适用于鼻子的每个解剖区域是错误的。因此,我们旨在通过应用两种不同结构类型的填充剂来开发一种混合治疗模式。根据透明质酸(HA)(一种亲水材料)和琼脂糖凝胶(AG)(一种非亲水且高G'值材料)的优缺点,在本研究中使用了这两种材料。

方法

在两年期间到办公室希望通过填充剂进行非手术隆鼻矫正的患者被纳入研究。在鼻尖定义点和鼻尖上方,每点皮内注射0.1毫升HA。分别在鼻根和鼻棘骨膜上注射0.4 - 0.7毫升和0.4 - 0.6毫升AG。两周后使用1至5分的全球美学改善量表评估临床改善情况(1:显著改善;5:患者情况恶化)。患者满意度采用0至10分制进行评估(0:不满意;10:非常满意)。

结果

共有32名患者(平均年龄:27岁)纳入研究。注射后患者满意度平均得分为9.09分(满分10分),两周后为9分(满分10分)。注射后在全球美学改善量表上的临床评估分数分别为1.72分(满分5分)和1.69分(满分5分)。未观察到重大并发症。

结论

在不同解剖位置应用的HA和AG填充剂混合概念是非手术隆鼻手术的一种安全且便捷的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45c/8987220/20547ffcb2ed/gox-10-e4236-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45c/8987220/f8efb4b8a2a5/gox-10-e4236-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45c/8987220/20547ffcb2ed/gox-10-e4236-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45c/8987220/f8efb4b8a2a5/gox-10-e4236-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45c/8987220/20547ffcb2ed/gox-10-e4236-g003.jpg

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2
Filler Migration to the Orbit.填充物向眼眶迁移。
Aesthet Surg J. 2021 May 18;41(6):NP559-NP566. doi: 10.1093/asj/sjaa264.
3
A new nonhydrophilic agarose gel as subdermal filler for facial rejuvenation: Aesthetic results and patient satisfaction.一种用于面部年轻化的新型非亲水性皮下填充琼脂糖凝胶:美学效果与患者满意度。
J Cosmet Dermatol. 2020 Aug;19(8):1900-1906. doi: 10.1111/jocd.13529. Epub 2020 Jun 20.
4
The use of algeness in the face and neck: a safe, alternative filler for cosmetics and reconstruction.藻酸盐在面部和颈部的应用:一种用于美容和重建的安全替代填充剂。
Ann Transl Med. 2020 Mar;8(6):362. doi: 10.21037/atm.2020.02.52.
5
Hyaluronic acid applications in ophthalmology, rheumatology, and dermatology.透明质酸在眼科、风湿病学和皮肤病学中的应用。
Carbohydr Res. 2020 Mar;489:107950. doi: 10.1016/j.carres.2020.107950. Epub 2020 Feb 18.
6
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7
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8
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