Nichols Justin, Eppes Stephen
PGY-4 Internal Medicine-Pediatrics Resident, ChristianaCare.
Director, Pediatric Infectious Disease; Director, Quality Assurance and Performance Improvement, ChristianaCare; Co-Chair, Immunization Coalition of Delaware.
Dela J Public Health. 2022 Mar 29;8(1):76-78. doi: 10.32481/djph.2022.03.012. eCollection 2022 Mar.
Neisseria meningitidis is an aerobic, gram-negative, diplococcus bacterium that is a leading cause of meningitis and sepsis in the United States. Particularly at-risk groups include those with complement deficiencies, people using complement inhibitors, individuals with anatomic or functional asplenia, patients with HIV infection and travelers to endemic countries. There are currently three quadrivalent meningococcal vaccines (Serogroups A, C, W, Y) and two recombinant serogroup B vaccines available for use in the United States, and recommendations for vaccine use have changed rapidly in the past 10-15 years. This article summarizes updated ACIP recommendations for meningococcal vaccination for the primary care provider.
脑膜炎奈瑟菌是一种需氧的革兰氏阴性双球菌,是美国脑膜炎和败血症的主要病因。特别高危的人群包括补体缺乏者、使用补体抑制剂的人、有解剖学或功能性无脾症的个体、艾滋病毒感染者以及前往流行国家的旅行者。目前在美国有三种四价脑膜炎球菌疫苗(A、C、W、Y血清群)和两种重组B血清群疫苗可供使用,并且在过去10至15年中疫苗使用建议变化迅速。本文总结了美国疾病控制与预防中心免疫实践咨询委员会(ACIP)针对初级保健提供者的脑膜炎球菌疫苗接种的最新建议。